| Full name: family with sequence similarity 181 member A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 90050 | HGNC ID: HGNC:20491 | Ensembl Gene: ENSG00000140067 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM181A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM181A | 90050 | 231117_at | 0.0792 | 0.8109 | |
| GSE26886 | FAM181A | 90050 | 231117_at | 0.2827 | 0.0280 | |
| GSE45670 | FAM181A | 90050 | 231117_at | 0.1562 | 0.0860 | |
| GSE53622 | FAM181A | 90050 | 63013 | 0.7950 | 0.0000 | |
| GSE53624 | FAM181A | 90050 | 63013 | 0.6657 | 0.0000 | |
| GSE63941 | FAM181A | 90050 | 231117_at | 0.2186 | 0.5067 | |
| GSE77861 | FAM181A | 90050 | 231117_at | -0.0470 | 0.7184 | |
| GSE97050 | FAM181A | 90050 | A_23_P117380 | 0.1912 | 0.3719 | |
| TCGA | FAM181A | 90050 | RNAseq | 0.9687 | 0.2204 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM181A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM181A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM181A | 90050 | 8 | 4 | 18 | |
| GSE20123 | FAM181A | 90050 | 8 | 3 | 19 | |
| GSE43470 | FAM181A | 90050 | 7 | 3 | 33 | |
| GSE46452 | FAM181A | 90050 | 16 | 3 | 40 | |
| GSE47630 | FAM181A | 90050 | 11 | 8 | 21 | |
| GSE54993 | FAM181A | 90050 | 3 | 8 | 59 | |
| GSE54994 | FAM181A | 90050 | 20 | 4 | 29 | |
| GSE60625 | FAM181A | 90050 | 0 | 2 | 9 | |
| GSE74703 | FAM181A | 90050 | 6 | 3 | 27 | |
| GSE74704 | FAM181A | 90050 | 4 | 3 | 13 | |
| TCGA | FAM181A | 90050 | 29 | 21 | 46 |
Total number of gains: 112; Total number of losses: 62; Total Number of normals: 314.
Somatic mutations of FAM181A:
Generating mutation plots.
Highly correlated genes for FAM181A:
Showing top 20/393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM181A | ST8SIA3 | 0.797323 | 3 | 0 | 3 |
| FAM181A | DEFB121 | 0.792059 | 3 | 0 | 3 |
| FAM181A | MS4A18 | 0.768763 | 3 | 0 | 3 |
| FAM181A | SLC26A1 | 0.76817 | 3 | 0 | 3 |
| FAM181A | LRCH4 | 0.762585 | 3 | 0 | 3 |
| FAM181A | C2orf72 | 0.760935 | 3 | 0 | 3 |
| FAM181A | OR2A5 | 0.760472 | 3 | 0 | 3 |
| FAM181A | VEPH1 | 0.756091 | 3 | 0 | 3 |
| FAM181A | GPR182 | 0.749604 | 3 | 0 | 3 |
| FAM181A | CES3 | 0.747684 | 3 | 0 | 3 |
| FAM181A | DCDC1 | 0.746865 | 3 | 0 | 3 |
| FAM181A | C20orf141 | 0.745961 | 4 | 0 | 4 |
| FAM181A | IQCH | 0.738512 | 3 | 0 | 3 |
| FAM181A | BBC3 | 0.73822 | 3 | 0 | 3 |
| FAM181A | NTNG2 | 0.737779 | 5 | 0 | 5 |
| FAM181A | CDKL4 | 0.73761 | 3 | 0 | 3 |
| FAM181A | MC1R | 0.737135 | 3 | 0 | 3 |
| FAM181A | GRIPAP1 | 0.735532 | 3 | 0 | 3 |
| FAM181A | IFITM5 | 0.733144 | 3 | 0 | 3 |
| FAM181A | PGAM2 | 0.732907 | 3 | 0 | 3 |
For details and further investigation, click here
