APOF

 

Full name: apolipoprotein F Alias Symbol: 
Type: protein-coding gene Cytoband: 12q13.3
Entrez ID: 319 HGNC ID: HGNC:615 Ensembl Gene: ENSG00000175336 OMIM ID: 107760
Drug and gene relationship at DGIdb

 

Expression of APOF:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 APOF 319 207262_at 0.0592 0.7760
GSE20347 APOF 319 207262_at 0.0123 0.7920
GSE23400 APOF 319 207262_at 0.0008 0.9591
GSE26886 APOF 319 207262_at 0.1026 0.2330
GSE29001 APOF 319 207262_at 0.1794 0.1547
GSE38129 APOF 319 207262_at -0.0301 0.5412
GSE45670 APOF 319 207262_at 0.0188 0.8372
GSE53622 APOF 319 145262 0.2147 0.1159
GSE53624 APOF 319 145262 -0.3741 0.0001
GSE63941 APOF 319 207262_at 0.0233 0.8789
GSE77861 APOF 319 207262_at 0.0217 0.8390
SRP133303 APOF 319 RNAseq 0.3412 0.1552
TCGA APOF 319 RNAseq 2.0450 0.1442

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by APOF expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of APOF:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 APOF 319 7 2 21
GSE20123 APOF 319 7 1 22
GSE43470 APOF 319 4 0 39
GSE46452 APOF 319 8 1 50
GSE47630 APOF 319 10 2 28
GSE54993 APOF 319 0 5 65
GSE54994 APOF 319 4 1 48
GSE60625 APOF 319 0 0 11
GSE74703 APOF 319 4 0 32
GSE74704 APOF 319 4 1 15
TCGA APOF 319 14 10 72

Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.  


 

Somatic mutations of APOF:

 

Generating mutation plots.

 

Highly correlated genes for APOF:

 

Showing top 20/33 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
APOFLIN28A0.758303
APOFNPTX10.729726303
APOFRNF50.648108303
APOFRARRES10.64502303
APOFSAFB20.643698303
APOFOR10C10.630379303
APOFC90.608036403
APOFORM10.589288503
APOFTFAP40.585411303
APOFIQCC0.574476403
APOFAPLP10.571793403
APOFSOHLH10.568511403
APOFHGD0.562228503
APOFOXCT20.558765404
APOFLINC013610.556311303
APOFREG3A0.553488403
APOFTP53I110.551109403
APOFNLGN4Y0.550248303
APOFTEX140.548418403
APOFPRAC10.545408403

For details and further investigation, click here