PRDM7

 

Full name: PR/SET domain 7 Alias Symbol: ZNF910
Type: protein-coding gene Cytoband: 16q24.3
Entrez ID: 11105 HGNC ID: HGNC:9351 Ensembl Gene: ENSG00000126856 OMIM ID: 609759
Drug and gene relationship at DGIdb

 

Expression of PRDM7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRDM7 11105 224228_s_at -0.0157 0.9568
GSE26886 PRDM7 11105 224228_s_at 0.0361 0.7231
GSE45670 PRDM7 11105 224228_s_at 0.1105 0.2323
GSE53622 PRDM7 11105 5071 0.0219 0.9106
GSE53624 PRDM7 11105 5071 0.1364 0.2376
GSE63941 PRDM7 11105 224228_s_at 0.2249 0.0769
GSE77861 PRDM7 11105 224228_s_at -0.0002 0.9982
SRP133303 PRDM7 11105 RNAseq -0.1174 0.5225
SRP159526 PRDM7 11105 RNAseq 0.5747 0.3812
SRP193095 PRDM7 11105 RNAseq 0.1048 0.5447
SRP219564 PRDM7 11105 RNAseq 0.0696 0.9042
TCGA PRDM7 11105 RNAseq 0.6918 0.5745

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PRDM7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PRDM7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRDM7 11105 4 3 23
GSE20123 PRDM7 11105 4 3 23
GSE43470 PRDM7 11105 1 13 29
GSE46452 PRDM7 11105 38 1 20
GSE47630 PRDM7 11105 11 9 20
GSE54993 PRDM7 11105 3 4 63
GSE54994 PRDM7 11105 9 11 33
GSE60625 PRDM7 11105 4 0 7
GSE74703 PRDM7 11105 1 9 26
GSE74704 PRDM7 11105 3 1 16
TCGA PRDM7 11105 26 15 55

Total number of gains: 104; Total number of losses: 69; Total Number of normals: 315.  

 

Somatic mutations of PRDM7:

 

Generating mutation plots.

 

Highly correlated genes for PRDM7:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRDM7PPEF20.628259303
PRDM7GOLGA6L60.612793403
PRDM7CA30.588572303
PRDM7LINC004940.583055303

For details and further investigation, click here