| Full name: protein phosphatase with EF-hand domain 2 | Alias Symbol: PPP7CB | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 5470 | HGNC ID: HGNC:9244 | Ensembl Gene: ENSG00000156194 | OMIM ID: 602256 |
| Drug and gene relationship at DGIdb | |||
Expression of PPEF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPEF2 | 5470 | 208411_x_at | 0.0513 | 0.8087 | |
| GSE20347 | PPEF2 | 5470 | 208411_x_at | 0.0155 | 0.8080 | |
| GSE23400 | PPEF2 | 5470 | 208411_x_at | -0.0154 | 0.3800 | |
| GSE26886 | PPEF2 | 5470 | 208411_x_at | 0.0165 | 0.8926 | |
| GSE29001 | PPEF2 | 5470 | 208411_x_at | -0.0355 | 0.8295 | |
| GSE38129 | PPEF2 | 5470 | 208411_x_at | -0.0326 | 0.5305 | |
| GSE45670 | PPEF2 | 5470 | 208411_x_at | 0.0382 | 0.5109 | |
| GSE53622 | PPEF2 | 5470 | 18857 | 0.0230 | 0.9096 | |
| GSE53624 | PPEF2 | 5470 | 18857 | -1.1439 | 0.0000 | |
| GSE63941 | PPEF2 | 5470 | 208411_x_at | 0.0545 | 0.6691 | |
| GSE77861 | PPEF2 | 5470 | 208411_x_at | -0.0440 | 0.5495 | |
| SRP133303 | PPEF2 | 5470 | RNAseq | 0.1461 | 0.5864 | |
| TCGA | PPEF2 | 5470 | RNAseq | 0.8144 | 0.5951 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PPEF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPEF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPEF2 | 5470 | 2 | 9 | 19 | |
| GSE20123 | PPEF2 | 5470 | 2 | 9 | 19 | |
| GSE43470 | PPEF2 | 5470 | 0 | 13 | 30 | |
| GSE46452 | PPEF2 | 5470 | 2 | 35 | 22 | |
| GSE47630 | PPEF2 | 5470 | 1 | 19 | 20 | |
| GSE54993 | PPEF2 | 5470 | 7 | 0 | 63 | |
| GSE54994 | PPEF2 | 5470 | 1 | 9 | 43 | |
| GSE60625 | PPEF2 | 5470 | 0 | 0 | 11 | |
| GSE74703 | PPEF2 | 5470 | 0 | 11 | 25 | |
| GSE74704 | PPEF2 | 5470 | 2 | 5 | 13 | |
| TCGA | PPEF2 | 5470 | 17 | 30 | 49 |
Total number of gains: 34; Total number of losses: 140; Total Number of normals: 314.
Somatic mutations of PPEF2:
Generating mutation plots.
Highly correlated genes for PPEF2:
Showing top 20/138 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPEF2 | OR2J2 | 0.664076 | 4 | 0 | 3 |
| PPEF2 | ANKRD1 | 0.657381 | 4 | 0 | 4 |
| PPEF2 | SLC9C2 | 0.65454 | 3 | 0 | 3 |
| PPEF2 | HTR1F | 0.647445 | 3 | 0 | 3 |
| PPEF2 | LINC00474 | 0.640398 | 4 | 0 | 4 |
| PPEF2 | PRDM7 | 0.628259 | 3 | 0 | 3 |
| PPEF2 | KRT38 | 0.626238 | 4 | 0 | 3 |
| PPEF2 | STS | 0.622975 | 3 | 0 | 3 |
| PPEF2 | DEFA4 | 0.619169 | 5 | 0 | 4 |
| PPEF2 | SCOC-AS1 | 0.617772 | 3 | 0 | 3 |
| PPEF2 | NR0B2 | 0.616801 | 4 | 0 | 3 |
| PPEF2 | CD226 | 0.603891 | 3 | 0 | 3 |
| PPEF2 | IL9 | 0.601465 | 5 | 0 | 4 |
| PPEF2 | TMEM235 | 0.600821 | 3 | 0 | 3 |
| PPEF2 | SLC5A4 | 0.600132 | 5 | 0 | 4 |
| PPEF2 | CER1 | 0.595694 | 4 | 0 | 3 |
| PPEF2 | ADAM30 | 0.595049 | 6 | 0 | 3 |
| PPEF2 | HTR1A | 0.593177 | 4 | 0 | 3 |
| PPEF2 | KIAA0087 | 0.592421 | 6 | 0 | 5 |
| PPEF2 | CLEC1B | 0.590913 | 5 | 0 | 3 |
For details and further investigation, click here
