SMTNL1

 

Full name: smoothelin like 1 Alias Symbol: CHASM
Type: protein-coding gene Cytoband: 11q12.1
Entrez ID: 219537 HGNC ID: HGNC:32394 Ensembl Gene: ENSG00000214872 OMIM ID: 613664
Drug and gene relationship at DGIdb

 

Expression of SMTNL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SMTNL1 219537 230367_at 0.0735 0.7501
GSE26886 SMTNL1 219537 230367_at -0.0374 0.8082
GSE45670 SMTNL1 219537 230367_at -0.0082 0.9353
GSE63941 SMTNL1 219537 230367_at 0.1008 0.7648
GSE77861 SMTNL1 219537 230367_at -0.1224 0.2328
GSE97050 SMTNL1 A_21_P0000005 -0.0685 0.7392
SRP133303 SMTNL1 219537 RNAseq 0.9338 0.0525
SRP159526 SMTNL1 219537 RNAseq 1.2159 0.1385
SRP219564 SMTNL1 219537 RNAseq 1.7013 0.0415
TCGA SMTNL1 219537 RNAseq 1.3286 0.0007

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by SMTNL1 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of SMTNL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SMTNL1 219537 2 3 25
GSE20123 SMTNL1 219537 2 3 25
GSE43470 SMTNL1 219537 1 5 37
GSE46452 SMTNL1 219537 9 4 46
GSE47630 SMTNL1 219537 3 8 29
GSE54993 SMTNL1 219537 3 0 67
GSE54994 SMTNL1 219537 5 6 42
GSE60625 SMTNL1 219537 0 3 8
GSE74703 SMTNL1 219537 1 3 32
GSE74704 SMTNL1 219537 2 3 15
TCGA SMTNL1 219537 14 10 72

Total number of gains: 42; Total number of losses: 48; Total Number of normals: 398.  

 

Somatic mutations of SMTNL1:

 

Generating mutation plots.

 

Highly correlated genes for SMTNL1:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SMTNL1OR51B20.645178303
SMTNL1EPHA100.6004303
SMTNL1TAS2R30.594327503
SMTNL1FAM181A-AS10.555222303
SMTNL1GPLD10.548191403

For details and further investigation, click here