| Full name: glycosylphosphatidylinositol specific phospholipase D1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 2822 | HGNC ID: HGNC:4459 | Ensembl Gene: ENSG00000112293 | OMIM ID: 602515 |
| Drug and gene relationship at DGIdb | |||
Expression of GPLD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPLD1 | 2822 | 206266_at | -0.0767 | 0.7793 | |
| GSE20347 | GPLD1 | 2822 | 206266_at | 0.0017 | 0.9845 | |
| GSE23400 | GPLD1 | 2822 | 206264_at | -0.1583 | 0.0016 | |
| GSE26886 | GPLD1 | 2822 | 206266_at | -0.1274 | 0.3946 | |
| GSE29001 | GPLD1 | 2822 | 206264_at | -0.1689 | 0.4622 | |
| GSE38129 | GPLD1 | 2822 | 206266_at | -0.1050 | 0.1737 | |
| GSE45670 | GPLD1 | 2822 | 206266_at | -0.0368 | 0.7531 | |
| GSE53622 | GPLD1 | 2822 | 59590 | -0.2091 | 0.0757 | |
| GSE53624 | GPLD1 | 2822 | 59590 | -0.0732 | 0.3317 | |
| GSE63941 | GPLD1 | 2822 | 206266_at | 0.2280 | 0.0985 | |
| GSE77861 | GPLD1 | 2822 | 206266_at | -0.1548 | 0.1053 | |
| GSE97050 | GPLD1 | 2822 | A_33_P3375467 | 0.0902 | 0.9115 | |
| SRP064894 | GPLD1 | 2822 | RNAseq | -0.4413 | 0.0577 | |
| SRP133303 | GPLD1 | 2822 | RNAseq | -0.2472 | 0.1815 | |
| SRP159526 | GPLD1 | 2822 | RNAseq | 1.3531 | 0.0288 | |
| SRP193095 | GPLD1 | 2822 | RNAseq | -0.0289 | 0.8380 | |
| SRP219564 | GPLD1 | 2822 | RNAseq | 0.1392 | 0.8239 | |
| TCGA | GPLD1 | 2822 | RNAseq | -0.4890 | 0.1550 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GPLD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPLD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPLD1 | 2822 | 4 | 2 | 24 | |
| GSE20123 | GPLD1 | 2822 | 4 | 2 | 24 | |
| GSE43470 | GPLD1 | 2822 | 6 | 0 | 37 | |
| GSE46452 | GPLD1 | 2822 | 1 | 9 | 49 | |
| GSE47630 | GPLD1 | 2822 | 8 | 5 | 27 | |
| GSE54993 | GPLD1 | 2822 | 1 | 1 | 68 | |
| GSE54994 | GPLD1 | 2822 | 10 | 4 | 39 | |
| GSE60625 | GPLD1 | 2822 | 0 | 1 | 10 | |
| GSE74703 | GPLD1 | 2822 | 6 | 0 | 30 | |
| GSE74704 | GPLD1 | 2822 | 1 | 1 | 18 | |
| TCGA | GPLD1 | 2822 | 17 | 20 | 59 |
Total number of gains: 58; Total number of losses: 45; Total Number of normals: 385.
Somatic mutations of GPLD1:
Generating mutation plots.
Highly correlated genes for GPLD1:
Showing top 20/737 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPLD1 | LINC00922 | 0.764453 | 3 | 0 | 3 |
| GPLD1 | SLC6A5 | 0.738919 | 3 | 0 | 3 |
| GPLD1 | CGA | 0.720684 | 4 | 0 | 4 |
| GPLD1 | KCNMB2 | 0.712469 | 4 | 0 | 4 |
| GPLD1 | PRR34 | 0.711492 | 3 | 0 | 3 |
| GPLD1 | MAS1 | 0.710861 | 3 | 0 | 3 |
| GPLD1 | CA8 | 0.707753 | 3 | 0 | 3 |
| GPLD1 | FSHR | 0.707264 | 3 | 0 | 3 |
| GPLD1 | CRHR2 | 0.699734 | 3 | 0 | 3 |
| GPLD1 | NOS1 | 0.697987 | 4 | 0 | 4 |
| GPLD1 | FSCN3 | 0.695948 | 5 | 0 | 4 |
| GPLD1 | CLCA1 | 0.690876 | 5 | 0 | 4 |
| GPLD1 | MC4R | 0.681767 | 3 | 0 | 3 |
| GPLD1 | LGR5 | 0.675144 | 3 | 0 | 3 |
| GPLD1 | NTNG1 | 0.67326 | 3 | 0 | 3 |
| GPLD1 | ATXN8OS | 0.670246 | 3 | 0 | 3 |
| GPLD1 | SLC6A12 | 0.668966 | 3 | 0 | 3 |
| GPLD1 | PRL | 0.668854 | 3 | 0 | 3 |
| GPLD1 | TEX15 | 0.665288 | 4 | 0 | 4 |
| GPLD1 | ACSBG2 | 0.664442 | 5 | 0 | 5 |
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