| Full name: taste 2 receptor member 3 | Alias Symbol: T2R3 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 50831 | HGNC ID: HGNC:14910 | Ensembl Gene: ENSG00000127362 | OMIM ID: 604868 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAS2R3 | 50831 | 221456_at | 0.0462 | 0.8845 | |
| GSE20347 | TAS2R3 | 50831 | 221456_at | 0.0092 | 0.8932 | |
| GSE23400 | TAS2R3 | 50831 | 221456_at | -0.0886 | 0.0314 | |
| GSE26886 | TAS2R3 | 50831 | 221456_at | -0.1279 | 0.3410 | |
| GSE29001 | TAS2R3 | 50831 | 221456_at | -0.1380 | 0.3100 | |
| GSE38129 | TAS2R3 | 50831 | 221456_at | -0.0434 | 0.5543 | |
| GSE45670 | TAS2R3 | 50831 | 221456_at | 0.0628 | 0.5364 | |
| GSE63941 | TAS2R3 | 50831 | 221456_at | 0.1693 | 0.3163 | |
| GSE77861 | TAS2R3 | 50831 | 221456_at | -0.1489 | 0.0554 | |
| GSE97050 | TAS2R3 | 50831 | A_23_P20139 | 0.0211 | 0.9323 | |
| SRP133303 | TAS2R3 | 50831 | RNAseq | -0.0180 | 0.9534 | |
| TCGA | TAS2R3 | 50831 | RNAseq | -0.5777 | 0.4670 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAS2R3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R3 | 50831 | 5 | 2 | 23 | |
| GSE20123 | TAS2R3 | 50831 | 5 | 2 | 23 | |
| GSE43470 | TAS2R3 | 50831 | 2 | 4 | 37 | |
| GSE46452 | TAS2R3 | 50831 | 7 | 2 | 50 | |
| GSE47630 | TAS2R3 | 50831 | 6 | 7 | 27 | |
| GSE54993 | TAS2R3 | 50831 | 3 | 5 | 62 | |
| GSE54994 | TAS2R3 | 50831 | 5 | 8 | 40 | |
| GSE60625 | TAS2R3 | 50831 | 0 | 0 | 11 | |
| GSE74703 | TAS2R3 | 50831 | 2 | 4 | 30 | |
| GSE74704 | TAS2R3 | 50831 | 1 | 2 | 17 | |
| TCGA | TAS2R3 | 50831 | 29 | 23 | 44 |
Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.
Somatic mutations of TAS2R3:
Generating mutation plots.
Highly correlated genes for TAS2R3:
Showing top 20/617 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R3 | SULT2A1 | 0.748721 | 3 | 0 | 3 |
| TAS2R3 | RHAG | 0.730354 | 3 | 0 | 3 |
| TAS2R3 | LRRC31 | 0.724051 | 4 | 0 | 4 |
| TAS2R3 | PRSS50 | 0.7052 | 3 | 0 | 3 |
| TAS2R3 | KIR2DS5 | 0.702978 | 4 | 0 | 4 |
| TAS2R3 | MYOD1 | 0.701827 | 4 | 0 | 4 |
| TAS2R3 | MAGEA8 | 0.695357 | 4 | 0 | 4 |
| TAS2R3 | PRDM11 | 0.67906 | 5 | 0 | 5 |
| TAS2R3 | MAPK4 | 0.678004 | 3 | 0 | 3 |
| TAS2R3 | HRG | 0.676587 | 5 | 0 | 5 |
| TAS2R3 | NTNG1 | 0.67419 | 4 | 0 | 4 |
| TAS2R3 | GHSR | 0.672336 | 3 | 0 | 3 |
| TAS2R3 | ERN1 | 0.671805 | 4 | 0 | 4 |
| TAS2R3 | OSBPL7 | 0.666673 | 5 | 0 | 5 |
| TAS2R3 | ASIC4 | 0.66614 | 3 | 0 | 3 |
| TAS2R3 | CHAT | 0.661699 | 4 | 0 | 4 |
| TAS2R3 | KHDRBS2 | 0.659958 | 6 | 0 | 6 |
| TAS2R3 | TCP10L | 0.659256 | 3 | 0 | 3 |
| TAS2R3 | DEFA4 | 0.655427 | 5 | 0 | 5 |
| TAS2R3 | BTG4 | 0.651657 | 3 | 0 | 3 |
For details and further investigation, click here
