SYT16

 

Full name: synaptotagmin 16 Alias Symbol: yt14r|CHR14SYT|Strep14
Type: protein-coding gene Cytoband: 14q23.2
Entrez ID: 83851 HGNC ID: HGNC:23142 Ensembl Gene: ENSG00000139973 OMIM ID: 610950
Drug and gene relationship at DGIdb

 

Expression of SYT16:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SYT16 83851 1554797_at 0.0664 0.7523
GSE26886 SYT16 83851 1554797_at -0.1136 0.2069
GSE45670 SYT16 83851 1554797_at 0.0784 0.3851
GSE53622 SYT16 83851 45324 0.7735 0.0002
GSE53624 SYT16 83851 45324 0.3144 0.0425
GSE63941 SYT16 83851 1554797_at 0.0399 0.8584
GSE77861 SYT16 83851 1554797_at 0.0056 0.9526
SRP133303 SYT16 83851 RNAseq 0.3192 0.0607
SRP159526 SYT16 83851 RNAseq 2.3366 0.0003
SRP193095 SYT16 83851 RNAseq -0.2238 0.3840
SRP219564 SYT16 83851 RNAseq -0.4150 0.3490
TCGA SYT16 83851 RNAseq -1.2733 0.1122

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SYT16 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SYT16:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SYT16 83851 8 3 19
GSE20123 SYT16 83851 8 3 19
GSE43470 SYT16 83851 8 2 33
GSE46452 SYT16 83851 16 3 40
GSE47630 SYT16 83851 11 9 20
GSE54993 SYT16 83851 3 9 58
GSE54994 SYT16 83851 19 4 30
GSE60625 SYT16 83851 0 2 9
GSE74703 SYT16 83851 7 2 27
GSE74704 SYT16 83851 4 2 14
TCGA SYT16 83851 33 14 49

Total number of gains: 117; Total number of losses: 53; Total Number of normals: 318.  

 

Somatic mutations of SYT16:

 

Generating mutation plots.

 

Highly correlated genes for SYT16:

 

Showing all 3 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SYT16PSG30.619275403
SYT16LLGL10.55224303
SYT16PSG60.530638303

For details and further investigation, click here