| Full name: pregnancy specific beta-1-glycoprotein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 5671 | HGNC ID: HGNC:9520 | Ensembl Gene: ENSG00000221826 | OMIM ID: 176392 |
| Drug and gene relationship at DGIdb | |||
Expression of PSG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSG3 | 5671 | 211741_x_at | -0.0275 | 0.9129 | |
| GSE20347 | PSG3 | 5671 | 211741_x_at | 0.1084 | 0.0829 | |
| GSE23400 | PSG3 | 5671 | 211741_x_at | -0.0224 | 0.3454 | |
| GSE26886 | PSG3 | 5671 | 211741_x_at | -0.0844 | 0.4304 | |
| GSE29001 | PSG3 | 5671 | 211741_x_at | -0.1603 | 0.3118 | |
| GSE38129 | PSG3 | 5671 | 211741_x_at | 0.0623 | 0.1971 | |
| GSE45670 | PSG3 | 5671 | 211741_x_at | 0.1569 | 0.3586 | |
| GSE53622 | PSG3 | 5671 | 74718 | 0.4646 | 0.0675 | |
| GSE53624 | PSG3 | 5671 | 74718 | 0.0031 | 0.9888 | |
| GSE63941 | PSG3 | 5671 | 211741_x_at | -0.2548 | 0.6877 | |
| GSE77861 | PSG3 | 5671 | 211741_x_at | 0.0311 | 0.8026 | |
| TCGA | PSG3 | 5671 | RNAseq | 1.2164 | 0.5385 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSG3 | 5671 | 6 | 5 | 19 | |
| GSE20123 | PSG3 | 5671 | 5 | 4 | 21 | |
| GSE43470 | PSG3 | 5671 | 5 | 11 | 27 | |
| GSE46452 | PSG3 | 5671 | 46 | 1 | 12 | |
| GSE47630 | PSG3 | 5671 | 8 | 6 | 26 | |
| GSE54993 | PSG3 | 5671 | 17 | 4 | 49 | |
| GSE54994 | PSG3 | 5671 | 7 | 12 | 34 | |
| GSE60625 | PSG3 | 5671 | 9 | 0 | 2 | |
| GSE74703 | PSG3 | 5671 | 5 | 7 | 24 | |
| GSE74704 | PSG3 | 5671 | 4 | 2 | 14 | |
| TCGA | PSG3 | 5671 | 14 | 15 | 67 |
Total number of gains: 126; Total number of losses: 67; Total Number of normals: 295.
Somatic mutations of PSG3:
Generating mutation plots.
Highly correlated genes for PSG3:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSG3 | SNTG1 | 0.699003 | 3 | 0 | 3 |
| PSG3 | HTR1D | 0.69478 | 3 | 0 | 3 |
| PSG3 | ZPBP2 | 0.680596 | 3 | 0 | 3 |
| PSG3 | LYPLA2 | 0.643517 | 3 | 0 | 3 |
| PSG3 | CDC25C | 0.641185 | 3 | 0 | 3 |
| PSG3 | NAT2 | 0.639883 | 5 | 0 | 4 |
| PSG3 | PSG2 | 0.633895 | 9 | 0 | 6 |
| PSG3 | CA7 | 0.630618 | 6 | 0 | 5 |
| PSG3 | PPP1R14D | 0.627066 | 4 | 0 | 3 |
| PSG3 | GRAMD1B | 0.624796 | 4 | 0 | 3 |
| PSG3 | CNGB3 | 0.62119 | 4 | 0 | 3 |
| PSG3 | DNAJA4 | 0.620115 | 4 | 0 | 3 |
| PSG3 | SYT16 | 0.619275 | 4 | 0 | 3 |
| PSG3 | CYP2A7 | 0.617538 | 6 | 0 | 5 |
| PSG3 | PDZD3 | 0.617428 | 4 | 0 | 4 |
| PSG3 | RBFADN | 0.617303 | 3 | 0 | 3 |
| PSG3 | LDHAL6B | 0.614909 | 5 | 0 | 4 |
| PSG3 | ANKUB1 | 0.613934 | 4 | 0 | 3 |
| PSG3 | CDH9 | 0.611413 | 3 | 0 | 3 |
| PSG3 | SNAP25 | 0.608276 | 3 | 0 | 3 |
For details and further investigation, click here
