TREML4

 

Full name: triggering receptor expressed on myeloid cells like 4 Alias Symbol: TLT4
Type: protein-coding gene Cytoband: 6p21.1
Entrez ID: 285852 HGNC ID: HGNC:30807 Ensembl Gene: ENSG00000188056 OMIM ID: 614664
Drug and gene relationship at DGIdb

 

Expression of TREML4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TREML4 285852 1564052_at 0.1928 0.5315
GSE26886 TREML4 285852 1564052_at 0.1220 0.2876
GSE45670 TREML4 285852 1567558_at 0.1078 0.2974
GSE53622 TREML4 285852 35054 0.2531 0.2018
GSE53624 TREML4 285852 125511 0.9572 0.0000
GSE63941 TREML4 285852 1564052_at -0.3712 0.0505
GSE77861 TREML4 285852 1564052_at -0.0183 0.9050
TCGA TREML4 285852 RNAseq 2.9355 0.0025

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TREML4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TREML4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TREML4 285852 5 2 23
GSE20123 TREML4 285852 5 2 23
GSE43470 TREML4 285852 6 0 37
GSE46452 TREML4 285852 2 9 48
GSE47630 TREML4 285852 8 4 28
GSE54993 TREML4 285852 3 2 65
GSE54994 TREML4 285852 11 4 38
GSE60625 TREML4 285852 0 1 10
GSE74703 TREML4 285852 6 0 30
GSE74704 TREML4 285852 2 2 16
TCGA TREML4 285852 19 13 64

Total number of gains: 67; Total number of losses: 39; Total Number of normals: 382.  

 

Somatic mutations of TREML4:

 

Generating mutation plots.

 

Highly correlated genes for TREML4:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TREML4CDH180.594353303
TREML4CECR30.579914404
TREML4ALDH1L20.572168303
TREML4LYPD80.540917303

For details and further investigation, click here