| Full name: aldehyde dehydrogenase 1 family member L2 | Alias Symbol: FLJ38508|mtFDH | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 160428 | HGNC ID: HGNC:26777 | Ensembl Gene: ENSG00000136010 | OMIM ID: 613584 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDH1L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDH1L2 | 160428 | 231202_at | 0.3665 | 0.6731 | |
| GSE26886 | ALDH1L2 | 160428 | 1556841_a_at | 0.2168 | 0.0122 | |
| GSE45670 | ALDH1L2 | 160428 | 231202_at | 0.1696 | 0.8477 | |
| GSE53622 | ALDH1L2 | 160428 | 53974 | 1.2573 | 0.0000 | |
| GSE53624 | ALDH1L2 | 160428 | 7749 | 0.4521 | 0.0000 | |
| GSE63941 | ALDH1L2 | 160428 | 231202_at | -3.5770 | 0.0707 | |
| GSE77861 | ALDH1L2 | 160428 | 1559393_at | -0.1207 | 0.2481 | |
| GSE97050 | ALDH1L2 | 160428 | A_33_P3282634 | 0.8031 | 0.1019 | |
| SRP007169 | ALDH1L2 | 160428 | RNAseq | 4.8494 | 0.0000 | |
| SRP008496 | ALDH1L2 | 160428 | RNAseq | 4.1705 | 0.0000 | |
| SRP064894 | ALDH1L2 | 160428 | RNAseq | 1.4232 | 0.0001 | |
| SRP133303 | ALDH1L2 | 160428 | RNAseq | 1.2616 | 0.0005 | |
| SRP159526 | ALDH1L2 | 160428 | RNAseq | 1.6215 | 0.0005 | |
| SRP193095 | ALDH1L2 | 160428 | RNAseq | 1.8179 | 0.0000 | |
| SRP219564 | ALDH1L2 | 160428 | RNAseq | 0.8167 | 0.1587 | |
| TCGA | ALDH1L2 | 160428 | RNAseq | -0.2477 | 0.1526 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by ALDH1L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDH1L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDH1L2 | 160428 | 4 | 2 | 24 | |
| GSE20123 | ALDH1L2 | 160428 | 4 | 2 | 24 | |
| GSE43470 | ALDH1L2 | 160428 | 2 | 0 | 41 | |
| GSE46452 | ALDH1L2 | 160428 | 9 | 1 | 49 | |
| GSE47630 | ALDH1L2 | 160428 | 9 | 1 | 30 | |
| GSE54993 | ALDH1L2 | 160428 | 0 | 5 | 65 | |
| GSE54994 | ALDH1L2 | 160428 | 4 | 2 | 47 | |
| GSE60625 | ALDH1L2 | 160428 | 0 | 0 | 11 | |
| GSE74703 | ALDH1L2 | 160428 | 2 | 0 | 34 | |
| GSE74704 | ALDH1L2 | 160428 | 1 | 2 | 17 | |
| TCGA | ALDH1L2 | 160428 | 19 | 10 | 67 |
Total number of gains: 54; Total number of losses: 25; Total Number of normals: 409.
Somatic mutations of ALDH1L2:
Generating mutation plots.
Highly correlated genes for ALDH1L2:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDH1L2 | PLEKHA4 | 0.742798 | 3 | 0 | 3 |
| ALDH1L2 | GLIS2 | 0.730545 | 4 | 0 | 3 |
| ALDH1L2 | PCBP3 | 0.727283 | 3 | 0 | 3 |
| ALDH1L2 | ADAMTSL5 | 0.723196 | 3 | 0 | 3 |
| ALDH1L2 | ICA1L | 0.717443 | 3 | 0 | 3 |
| ALDH1L2 | C2CD4B | 0.711309 | 3 | 0 | 3 |
| ALDH1L2 | HIF1A | 0.709643 | 3 | 0 | 3 |
| ALDH1L2 | INSRR | 0.708562 | 3 | 0 | 3 |
| ALDH1L2 | CLDND2 | 0.708169 | 3 | 0 | 3 |
| ALDH1L2 | TBC1D19 | 0.706742 | 3 | 0 | 3 |
| ALDH1L2 | LIX1L | 0.704989 | 3 | 0 | 3 |
| ALDH1L2 | COL8A2 | 0.700702 | 4 | 0 | 3 |
| ALDH1L2 | NBAS | 0.684707 | 4 | 0 | 3 |
| ALDH1L2 | MATN4 | 0.684459 | 3 | 0 | 3 |
| ALDH1L2 | ZNF358 | 0.684154 | 3 | 0 | 3 |
| ALDH1L2 | ZNF771 | 0.683682 | 3 | 0 | 3 |
| ALDH1L2 | PTGER3 | 0.680367 | 3 | 0 | 3 |
| ALDH1L2 | GPX8 | 0.676574 | 5 | 0 | 4 |
| ALDH1L2 | FOXC2 | 0.673488 | 3 | 0 | 3 |
| ALDH1L2 | PROCR | 0.666091 | 4 | 0 | 4 |
For details and further investigation, click here
