| Full name: cadherin 18 | Alias Symbol: CDH14|EY-CADHERIN | ||
| Type: protein-coding gene | Cytoband: 5p14.3 | ||
| Entrez ID: 1016 | HGNC ID: HGNC:1757 | Ensembl Gene: ENSG00000145526 | OMIM ID: 603019 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH18 | 1016 | 206280_at | 0.4931 | 0.5714 | |
| GSE20347 | CDH18 | 1016 | 206280_at | 0.0753 | 0.2894 | |
| GSE23400 | CDH18 | 1016 | 206280_at | -0.1221 | 0.0060 | |
| GSE26886 | CDH18 | 1016 | 206280_at | 0.0140 | 0.8999 | |
| GSE29001 | CDH18 | 1016 | 206280_at | 0.0430 | 0.8706 | |
| GSE38129 | CDH18 | 1016 | 206280_at | 0.0841 | 0.5789 | |
| GSE45670 | CDH18 | 1016 | 206280_at | 0.3341 | 0.4026 | |
| GSE53622 | CDH18 | 1016 | 60115 | 0.3333 | 0.1215 | |
| GSE53624 | CDH18 | 1016 | 60115 | 0.5777 | 0.0076 | |
| GSE63941 | CDH18 | 1016 | 206280_at | 0.3947 | 0.5571 | |
| GSE77861 | CDH18 | 1016 | 206280_at | -0.0981 | 0.4803 | |
| SRP133303 | CDH18 | 1016 | RNAseq | 1.4327 | 0.0086 | |
| TCGA | CDH18 | 1016 | RNAseq | 1.6022 | 0.2284 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CDH18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH18 | 1016 | 9 | 0 | 21 | |
| GSE20123 | CDH18 | 1016 | 9 | 0 | 21 | |
| GSE43470 | CDH18 | 1016 | 17 | 0 | 26 | |
| GSE46452 | CDH18 | 1016 | 6 | 22 | 31 | |
| GSE47630 | CDH18 | 1016 | 6 | 11 | 23 | |
| GSE54993 | CDH18 | 1016 | 5 | 5 | 60 | |
| GSE54994 | CDH18 | 1016 | 29 | 2 | 22 | |
| GSE60625 | CDH18 | 1016 | 0 | 0 | 11 | |
| GSE74703 | CDH18 | 1016 | 13 | 0 | 23 | |
| GSE74704 | CDH18 | 1016 | 8 | 0 | 12 | |
| TCGA | CDH18 | 1016 | 58 | 3 | 35 |
Total number of gains: 160; Total number of losses: 43; Total Number of normals: 285.
Somatic mutations of CDH18:
Generating mutation plots.
Highly correlated genes for CDH18:
Showing top 20/138 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH18 | MAGEC2 | 0.714165 | 4 | 0 | 4 |
| CDH18 | MYOZ3 | 0.685815 | 4 | 0 | 4 |
| CDH18 | PON1 | 0.685069 | 4 | 0 | 3 |
| CDH18 | TDRKH | 0.664138 | 3 | 0 | 3 |
| CDH18 | SAGE1 | 0.648205 | 4 | 0 | 3 |
| CDH18 | ZMAT4 | 0.647218 | 4 | 0 | 4 |
| CDH18 | CYSLTR2 | 0.642285 | 3 | 0 | 3 |
| CDH18 | TMPRSS15 | 0.640104 | 4 | 0 | 3 |
| CDH18 | RCVRN | 0.637746 | 3 | 0 | 3 |
| CDH18 | AMHR2 | 0.637535 | 3 | 0 | 3 |
| CDH18 | SEMA4G | 0.63689 | 3 | 0 | 3 |
| CDH18 | KIR2DL1 | 0.629863 | 3 | 0 | 3 |
| CDH18 | SLC30A3 | 0.62454 | 3 | 0 | 3 |
| CDH18 | NPY5R | 0.620539 | 3 | 0 | 3 |
| CDH18 | C2orf72 | 0.619852 | 4 | 0 | 3 |
| CDH18 | SLC35E3 | 0.61835 | 4 | 0 | 3 |
| CDH18 | PPM1E | 0.614852 | 4 | 0 | 3 |
| CDH18 | NTNG1 | 0.614569 | 3 | 0 | 3 |
| CDH18 | CYLC1 | 0.609559 | 3 | 0 | 3 |
| CDH18 | SYT13 | 0.608319 | 6 | 0 | 4 |
For details and further investigation, click here
