| Full name: LY6/PLAUR domain containing 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 646627 | HGNC ID: HGNC:44208 | Ensembl Gene: ENSG00000259823 | OMIM ID: 617067 |
| Drug and gene relationship at DGIdb | |||
Expression of LYPD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYPD8 | 646627 | 238143_at | 0.1327 | 0.7107 | |
| GSE26886 | LYPD8 | 646627 | 238143_at | -0.1380 | 0.3437 | |
| GSE45670 | LYPD8 | 646627 | 238143_at | 0.4265 | 0.0014 | |
| GSE53622 | LYPD8 | 646627 | 43203 | 0.5405 | 0.0020 | |
| GSE53624 | LYPD8 | 646627 | 43203 | 0.5493 | 0.0022 | |
| GSE63941 | LYPD8 | 646627 | 238143_at | 0.1248 | 0.5515 | |
| GSE77861 | LYPD8 | 646627 | 238143_at | -0.2261 | 0.0777 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LYPD8 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LYPD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPD8 | 646627 | 8 | 1 | 21 | |
| GSE20123 | LYPD8 | 646627 | 7 | 1 | 22 | |
| GSE43470 | LYPD8 | 646627 | 4 | 3 | 36 | |
| GSE46452 | LYPD8 | 646627 | 4 | 2 | 53 | |
| GSE47630 | LYPD8 | 646627 | 15 | 1 | 24 | |
| GSE54993 | LYPD8 | 646627 | 0 | 6 | 64 | |
| GSE54994 | LYPD8 | 646627 | 18 | 0 | 35 | |
| GSE60625 | LYPD8 | 646627 | 0 | 0 | 11 | |
| GSE74703 | LYPD8 | 646627 | 4 | 1 | 31 | |
| GSE74704 | LYPD8 | 646627 | 2 | 0 | 18 | |
| TCGA | LYPD8 | 646627 | 45 | 4 | 47 |
Total number of gains: 107; Total number of losses: 19; Total Number of normals: 362.
Somatic mutations of LYPD8:
Generating mutation plots.
Highly correlated genes for LYPD8:
Showing top 20/60 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPD8 | CACNA1G | 0.711959 | 3 | 0 | 3 |
| LYPD8 | TNP2 | 0.684465 | 3 | 0 | 3 |
| LYPD8 | ANKRD33 | 0.673723 | 3 | 0 | 3 |
| LYPD8 | SCARF1 | 0.669573 | 3 | 0 | 3 |
| LYPD8 | POLR3E | 0.667048 | 3 | 0 | 3 |
| LYPD8 | C20orf202 | 0.6576 | 3 | 0 | 3 |
| LYPD8 | LINC01270 | 0.653755 | 3 | 0 | 3 |
| LYPD8 | GAB4 | 0.648485 | 4 | 0 | 3 |
| LYPD8 | ZNF429 | 0.64235 | 3 | 0 | 3 |
| LYPD8 | KIF6 | 0.635055 | 3 | 0 | 3 |
| LYPD8 | GPR182 | 0.62928 | 3 | 0 | 3 |
| LYPD8 | LINC00691 | 0.623292 | 3 | 0 | 3 |
| LYPD8 | MYH2 | 0.622451 | 3 | 0 | 3 |
| LYPD8 | SLC17A9 | 0.620003 | 3 | 0 | 3 |
| LYPD8 | SLC22A24 | 0.616313 | 3 | 0 | 3 |
| LYPD8 | UROC1 | 0.610098 | 4 | 0 | 3 |
| LYPD8 | DPEP3 | 0.605435 | 4 | 0 | 4 |
| LYPD8 | ADAM12 | 0.603177 | 3 | 0 | 3 |
| LYPD8 | SLC12A1 | 0.60285 | 3 | 0 | 3 |
| LYPD8 | OR10H1 | 0.598847 | 4 | 0 | 3 |
For details and further investigation, click here
