UBE2U

 

Full name: ubiquitin conjugating enzyme E2 U Alias Symbol: MGC35130
Type: protein-coding gene Cytoband: 1p31.3
Entrez ID: 148581 HGNC ID: HGNC:28559 Ensembl Gene: ENSG00000177414 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of UBE2U:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UBE2U 148581 242392_at 0.1663 0.7026
GSE26886 UBE2U 148581 242392_at 0.0566 0.5563
GSE45670 UBE2U 148581 1553776_at 0.0977 0.1359
GSE53622 UBE2U 148581 101133 0.0690 0.7897
GSE53624 UBE2U 148581 101133 0.0624 0.7207
GSE63941 UBE2U 148581 242392_at 0.0466 0.7701
GSE77861 UBE2U 148581 242392_at 0.0627 0.6069
TCGA UBE2U 148581 RNAseq -2.1917 0.0807

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UBE2U expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of UBE2U:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UBE2U 148581 3 7 20
GSE20123 UBE2U 148581 3 6 21
GSE43470 UBE2U 148581 4 4 35
GSE46452 UBE2U 148581 0 1 58
GSE47630 UBE2U 148581 8 5 27
GSE54993 UBE2U 148581 0 0 70
GSE54994 UBE2U 148581 6 4 43
GSE60625 UBE2U 148581 0 0 11
GSE74703 UBE2U 148581 3 3 30
GSE74704 UBE2U 148581 2 3 15
TCGA UBE2U 148581 11 20 65

Total number of gains: 40; Total number of losses: 53; Total Number of normals: 395.  

 

Somatic mutations of UBE2U:

 

Generating mutation plots.

 

Highly correlated genes for UBE2U:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UBE2UNMBR0.584486303
UBE2UONECUT20.564373303
UBE2ULARP10.559794303
UBE2UARHGAP22-IT10.526145303
UBE2UZNF7060.523325303

For details and further investigation, click here