| Full name: La ribonucleoprotein domain family member 1 | Alias Symbol: LARP|KIAA0731|MGC19556 | ||
| Type: protein-coding gene | Cytoband: 5q33.2 | ||
| Entrez ID: 23367 | HGNC ID: HGNC:29531 | Ensembl Gene: ENSG00000155506 | OMIM ID: 612059 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LARP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LARP1 | 23367 | 212137_at | 0.3588 | 0.3413 | |
| GSE20347 | LARP1 | 23367 | 212137_at | -0.0483 | 0.7279 | |
| GSE23400 | LARP1 | 23367 | 212137_at | 0.2088 | 0.0025 | |
| GSE26886 | LARP1 | 23367 | 212137_at | 0.6063 | 0.0024 | |
| GSE29001 | LARP1 | 23367 | 212137_at | 0.2244 | 0.1927 | |
| GSE38129 | LARP1 | 23367 | 212137_at | 0.1282 | 0.2201 | |
| GSE45670 | LARP1 | 23367 | 212137_at | 0.1404 | 0.1881 | |
| GSE53622 | LARP1 | 23367 | 156762 | -0.1784 | 0.0040 | |
| GSE53624 | LARP1 | 23367 | 156762 | 0.0547 | 0.1886 | |
| GSE63941 | LARP1 | 23367 | 212137_at | 0.1378 | 0.6675 | |
| GSE77861 | LARP1 | 23367 | 212137_at | 0.2061 | 0.3216 | |
| GSE97050 | LARP1 | 23367 | A_23_P156319 | 0.1890 | 0.4469 | |
| SRP007169 | LARP1 | 23367 | RNAseq | -0.2653 | 0.4423 | |
| SRP008496 | LARP1 | 23367 | RNAseq | -0.5517 | 0.0083 | |
| SRP064894 | LARP1 | 23367 | RNAseq | -0.0271 | 0.8630 | |
| SRP133303 | LARP1 | 23367 | RNAseq | 0.1426 | 0.2001 | |
| SRP159526 | LARP1 | 23367 | RNAseq | -0.1068 | 0.7104 | |
| SRP193095 | LARP1 | 23367 | RNAseq | 0.1145 | 0.3264 | |
| SRP219564 | LARP1 | 23367 | RNAseq | 0.1991 | 0.5839 | |
| TCGA | LARP1 | 23367 | RNAseq | -0.0046 | 0.9060 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LARP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LARP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LARP1 | 23367 | 0 | 12 | 18 | |
| GSE20123 | LARP1 | 23367 | 0 | 12 | 18 | |
| GSE43470 | LARP1 | 23367 | 2 | 10 | 31 | |
| GSE46452 | LARP1 | 23367 | 0 | 27 | 32 | |
| GSE47630 | LARP1 | 23367 | 0 | 20 | 20 | |
| GSE54993 | LARP1 | 23367 | 9 | 1 | 60 | |
| GSE54994 | LARP1 | 23367 | 1 | 16 | 36 | |
| GSE60625 | LARP1 | 23367 | 0 | 0 | 11 | |
| GSE74703 | LARP1 | 23367 | 2 | 8 | 26 | |
| GSE74704 | LARP1 | 23367 | 0 | 7 | 13 | |
| TCGA | LARP1 | 23367 | 4 | 38 | 54 |
Total number of gains: 18; Total number of losses: 151; Total Number of normals: 319.
Somatic mutations of LARP1:
Generating mutation plots.
Highly correlated genes for LARP1:
Showing top 20/609 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LARP1 | GPATCH1 | 0.761019 | 3 | 0 | 3 |
| LARP1 | RNF149 | 0.75327 | 3 | 0 | 3 |
| LARP1 | DDX6 | 0.739087 | 3 | 0 | 3 |
| LARP1 | OPLAH | 0.738159 | 3 | 0 | 3 |
| LARP1 | EPN1 | 0.736556 | 3 | 0 | 3 |
| LARP1 | UAP1L1 | 0.725887 | 3 | 0 | 3 |
| LARP1 | CCDC85C | 0.725427 | 4 | 0 | 3 |
| LARP1 | TGFB1 | 0.720742 | 4 | 0 | 4 |
| LARP1 | NAIP | 0.719265 | 3 | 0 | 3 |
| LARP1 | ZNF319 | 0.718701 | 3 | 0 | 3 |
| LARP1 | QSOX2 | 0.714699 | 3 | 0 | 3 |
| LARP1 | ARL6IP6 | 0.714209 | 3 | 0 | 3 |
| LARP1 | ROMO1 | 0.710823 | 4 | 0 | 3 |
| LARP1 | TOMM40L | 0.707397 | 3 | 0 | 3 |
| LARP1 | RBM12B | 0.704758 | 3 | 0 | 3 |
| LARP1 | COG2 | 0.702529 | 3 | 0 | 3 |
| LARP1 | ARHGAP39 | 0.701335 | 3 | 0 | 3 |
| LARP1 | CCAR1 | 0.70101 | 3 | 0 | 3 |
| LARP1 | PPP1R9B | 0.700347 | 4 | 0 | 4 |
| LARP1 | IMMP1L | 0.699798 | 3 | 0 | 3 |
For details and further investigation, click here
