| Full name: neuromedin B receptor | Alias Symbol: BB1|BB1R | ||
| Type: protein-coding gene | Cytoband: 6q24.1 | ||
| Entrez ID: 4829 | HGNC ID: HGNC:7843 | Ensembl Gene: ENSG00000135577 | OMIM ID: 162341 |
| Drug and gene relationship at DGIdb | |||
Expression of NMBR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NMBR | 4829 | 207333_at | 0.0557 | 0.8726 | |
| GSE20347 | NMBR | 4829 | 207333_at | 0.1077 | 0.1213 | |
| GSE23400 | NMBR | 4829 | 207333_at | -0.0719 | 0.0671 | |
| GSE26886 | NMBR | 4829 | 207333_at | 0.1035 | 0.4051 | |
| GSE29001 | NMBR | 4829 | 207333_at | 0.0859 | 0.6299 | |
| GSE38129 | NMBR | 4829 | 207333_at | 0.0002 | 0.9982 | |
| GSE45670 | NMBR | 4829 | 207333_at | 0.0617 | 0.5162 | |
| GSE53622 | NMBR | 4829 | 36392 | -0.2157 | 0.1839 | |
| GSE53624 | NMBR | 4829 | 36392 | -0.1101 | 0.2544 | |
| GSE63941 | NMBR | 4829 | 207333_at | -0.1031 | 0.4037 | |
| GSE77861 | NMBR | 4829 | 207333_at | -0.0376 | 0.6285 | |
| TCGA | NMBR | 4829 | RNAseq | -0.9191 | 0.3887 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NMBR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NMBR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NMBR | 4829 | 2 | 5 | 23 | |
| GSE20123 | NMBR | 4829 | 2 | 3 | 25 | |
| GSE43470 | NMBR | 4829 | 5 | 0 | 38 | |
| GSE46452 | NMBR | 4829 | 3 | 10 | 46 | |
| GSE47630 | NMBR | 4829 | 9 | 4 | 27 | |
| GSE54993 | NMBR | 4829 | 3 | 2 | 65 | |
| GSE54994 | NMBR | 4829 | 8 | 8 | 37 | |
| GSE60625 | NMBR | 4829 | 0 | 1 | 10 | |
| GSE74703 | NMBR | 4829 | 4 | 0 | 32 | |
| GSE74704 | NMBR | 4829 | 0 | 2 | 18 | |
| TCGA | NMBR | 4829 | 11 | 19 | 66 |
Total number of gains: 47; Total number of losses: 54; Total Number of normals: 387.
Somatic mutations of NMBR:
Generating mutation plots.
Highly correlated genes for NMBR:
Showing top 20/428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NMBR | KCNV1 | 0.729318 | 3 | 0 | 3 |
| NMBR | SFTPB | 0.701426 | 4 | 0 | 4 |
| NMBR | OR1F1 | 0.696426 | 4 | 0 | 4 |
| NMBR | SLC6A12 | 0.685 | 4 | 0 | 4 |
| NMBR | DAB1 | 0.679855 | 4 | 0 | 4 |
| NMBR | KIR2DL4 | 0.666631 | 5 | 0 | 5 |
| NMBR | RPGRIP1 | 0.657952 | 4 | 0 | 3 |
| NMBR | NTNG1 | 0.646935 | 4 | 0 | 4 |
| NMBR | TMEM212 | 0.646547 | 3 | 0 | 3 |
| NMBR | HRG | 0.645602 | 4 | 0 | 4 |
| NMBR | CLCA1 | 0.644905 | 6 | 0 | 5 |
| NMBR | NOL4 | 0.64285 | 4 | 0 | 3 |
| NMBR | SLC35E1 | 0.641107 | 3 | 0 | 3 |
| NMBR | SLC17A1 | 0.641092 | 6 | 0 | 6 |
| NMBR | SLC10A1 | 0.63992 | 4 | 0 | 4 |
| NMBR | RFPL2 | 0.638909 | 5 | 0 | 4 |
| NMBR | OPHN1 | 0.638095 | 3 | 0 | 3 |
| NMBR | ATG10 | 0.637799 | 5 | 0 | 4 |
| NMBR | ZNF460 | 0.636661 | 4 | 0 | 3 |
| NMBR | PRODH2 | 0.634018 | 4 | 0 | 3 |
For details and further investigation, click here
