WDR88

 

Full name: WD repeat domain 88 Alias Symbol: 
Type: protein-coding gene Cytoband: 19q13.11
Entrez ID: 126248 HGNC ID: HGNC:26999 Ensembl Gene: ENSG00000166359 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of WDR88:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WDR88 126248 1552453_a_at -0.0446 0.8709
GSE26886 WDR88 126248 1552452_at 0.0902 0.2925
GSE45670 WDR88 126248 1552453_a_at 0.1359 0.0882
GSE53622 WDR88 126248 84696 -0.3361 0.0234
GSE53624 WDR88 126248 84696 0.0706 0.5999
GSE63941 WDR88 126248 1552453_a_at 0.2022 0.1248
GSE77861 WDR88 126248 1552452_at -0.0225 0.8094
SRP133303 WDR88 126248 RNAseq 0.3032 0.3441
SRP159526 WDR88 126248 RNAseq 1.1500 0.0021
SRP219564 WDR88 126248 RNAseq 0.5679 0.1611
TCGA WDR88 126248 RNAseq 0.2037 0.4901

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by WDR88 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of WDR88:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WDR88 126248 7 6 17
GSE20123 WDR88 126248 7 5 18
GSE43470 WDR88 126248 4 6 33
GSE46452 WDR88 126248 47 1 11
GSE47630 WDR88 126248 8 6 26
GSE54993 WDR88 126248 17 3 50
GSE54994 WDR88 126248 7 9 37
GSE60625 WDR88 126248 9 0 2
GSE74703 WDR88 126248 4 4 28
GSE74704 WDR88 126248 6 3 11
TCGA WDR88 126248 18 12 66

Total number of gains: 134; Total number of losses: 55; Total Number of normals: 299.  

 

Somatic mutations of WDR88:

 

Generating mutation plots.

 

Highly correlated genes for WDR88:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WDR88SIX60.595077303
WDR88NTSR10.582379303
WDR88OR8G10.572192403
WDR88BTBD170.511947503

For details and further investigation, click here