| Full name: neurotensin receptor 1 | Alias Symbol: NTR | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 4923 | HGNC ID: HGNC:8039 | Ensembl Gene: ENSG00000101188 | OMIM ID: 162651 |
| Drug and gene relationship at DGIdb | |||
NTSR1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway |
Expression of NTSR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NTSR1 | 4923 | 207360_s_at | 0.1796 | 0.6662 | |
| GSE20347 | NTSR1 | 4923 | 207360_s_at | -0.0159 | 0.8581 | |
| GSE23400 | NTSR1 | 4923 | 207360_s_at | -0.1439 | 0.0003 | |
| GSE26886 | NTSR1 | 4923 | 207360_s_at | 0.0797 | 0.5819 | |
| GSE29001 | NTSR1 | 4923 | 207360_s_at | -0.0761 | 0.6038 | |
| GSE38129 | NTSR1 | 4923 | 207360_s_at | -0.0751 | 0.3415 | |
| GSE45670 | NTSR1 | 4923 | 207360_s_at | 0.1493 | 0.1608 | |
| GSE63941 | NTSR1 | 4923 | 207360_s_at | -0.2050 | 0.3195 | |
| GSE77861 | NTSR1 | 4923 | 207360_s_at | 0.0237 | 0.8859 | |
| TCGA | NTSR1 | 4923 | RNAseq | -0.4577 | 0.4349 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NTSR1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NTSR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NTSR1 | 4923 | 14 | 2 | 14 | |
| GSE20123 | NTSR1 | 4923 | 14 | 2 | 14 | |
| GSE43470 | NTSR1 | 4923 | 11 | 1 | 31 | |
| GSE46452 | NTSR1 | 4923 | 35 | 0 | 24 | |
| GSE47630 | NTSR1 | 4923 | 25 | 1 | 14 | |
| GSE54993 | NTSR1 | 4923 | 0 | 17 | 53 | |
| GSE54994 | NTSR1 | 4923 | 29 | 0 | 24 | |
| GSE60625 | NTSR1 | 4923 | 0 | 0 | 11 | |
| GSE74703 | NTSR1 | 4923 | 10 | 0 | 26 | |
| GSE74704 | NTSR1 | 4923 | 11 | 0 | 9 | |
| TCGA | NTSR1 | 4923 | 43 | 4 | 49 |
Total number of gains: 192; Total number of losses: 27; Total Number of normals: 269.
Somatic mutations of NTSR1:
Generating mutation plots.
Highly correlated genes for NTSR1:
Showing top 20/106 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NTSR1 | BTBD17 | 0.648329 | 3 | 0 | 3 |
| NTSR1 | TIGD3 | 0.640254 | 3 | 0 | 3 |
| NTSR1 | ACTN3 | 0.617353 | 4 | 0 | 3 |
| NTSR1 | FAM153A | 0.616122 | 5 | 0 | 4 |
| NTSR1 | MAGEC2 | 0.614682 | 3 | 0 | 3 |
| NTSR1 | ZNF474 | 0.614297 | 3 | 0 | 3 |
| NTSR1 | CBL | 0.608768 | 4 | 0 | 3 |
| NTSR1 | HTR1B | 0.604564 | 4 | 0 | 3 |
| NTSR1 | IRS4 | 0.604307 | 4 | 0 | 3 |
| NTSR1 | RAPSN | 0.602784 | 3 | 0 | 3 |
| NTSR1 | PSG1 | 0.601614 | 3 | 0 | 3 |
| NTSR1 | TNFRSF10C | 0.599938 | 3 | 0 | 3 |
| NTSR1 | SNHG10 | 0.593724 | 4 | 0 | 3 |
| NTSR1 | FRMD5 | 0.591465 | 3 | 0 | 3 |
| NTSR1 | CRYGC | 0.587409 | 4 | 0 | 3 |
| NTSR1 | SIX6 | 0.584548 | 5 | 0 | 4 |
| NTSR1 | UMOD | 0.583422 | 3 | 0 | 3 |
| NTSR1 | TNFSF11 | 0.582777 | 5 | 0 | 4 |
| NTSR1 | WDR88 | 0.582379 | 3 | 0 | 3 |
| NTSR1 | GRIA3 | 0.582201 | 3 | 0 | 3 |
For details and further investigation, click here
