ZNF131

 

Full name: zinc finger protein 131 Alias Symbol: ZBTB35|pHZ-10
Type: protein-coding gene Cytoband: 5p12
Entrez ID: 7690 HGNC ID: HGNC:12915 Ensembl Gene: ENSG00000172262 OMIM ID: 604073
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ZNF131:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 ZNF131 7690 142193 0.2346 0.0004
GSE53624 ZNF131 7690 142193 0.3353 0.0000
GSE97050 ZNF131 7690 A_33_P3296074 0.1327 0.6430
SRP007169 ZNF131 7690 RNAseq 1.3242 0.0464
SRP008496 ZNF131 7690 RNAseq 0.8830 0.0435
SRP064894 ZNF131 7690 RNAseq 0.1941 0.4090
SRP133303 ZNF131 7690 RNAseq 0.5191 0.0025
SRP159526 ZNF131 7690 RNAseq 0.3225 0.2618
SRP193095 ZNF131 7690 RNAseq 0.0476 0.6954
SRP219564 ZNF131 7690 RNAseq 0.0801 0.7619
TCGA ZNF131 7690 RNAseq 0.2265 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by ZNF131 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZNF131:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF131 7690 10 0 20
GSE20123 ZNF131 7690 10 0 20
GSE43470 ZNF131 7690 17 0 26
GSE46452 ZNF131 7690 5 22 32
GSE47630 ZNF131 7690 6 12 22
GSE54993 ZNF131 7690 6 3 61
GSE54994 ZNF131 7690 24 2 27
GSE60625 ZNF131 7690 0 0 11
GSE74703 ZNF131 7690 13 0 23
GSE74704 ZNF131 7690 9 0 11
TCGA ZNF131 7690 53 6 37

Total number of gains: 153; Total number of losses: 45; Total Number of normals: 290.  

 

Somatic mutations of ZNF131:

 

Generating mutation plots.

 

Highly correlated genes for ZNF131:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF131MRPS300.722925303
ZNF131C5orf220.66647404
ZNF131UHRF1BP10.644682303
ZNF131WDR700.633637303
ZNF131NUP1550.543789403

For details and further investigation, click here