| Full name: WD repeat domain 70 | Alias Symbol: FLJ10233 | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 55100 | HGNC ID: HGNC:25495 | Ensembl Gene: ENSG00000082068 | OMIM ID: 617233 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR70:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR70 | 55100 | 219193_at | 0.2551 | 0.4571 | |
| GSE20347 | WDR70 | 55100 | 219193_at | 0.1716 | 0.1505 | |
| GSE23400 | WDR70 | 55100 | 219193_at | 0.0812 | 0.1009 | |
| GSE26886 | WDR70 | 55100 | 219193_at | 0.2898 | 0.1995 | |
| GSE29001 | WDR70 | 55100 | 219193_at | 0.0767 | 0.7787 | |
| GSE38129 | WDR70 | 55100 | 219193_at | 0.2848 | 0.0056 | |
| GSE45670 | WDR70 | 55100 | 219193_at | 0.0119 | 0.9490 | |
| GSE53622 | WDR70 | 55100 | 60164 | 0.1688 | 0.0343 | |
| GSE53624 | WDR70 | 55100 | 60164 | 0.2853 | 0.0000 | |
| GSE63941 | WDR70 | 55100 | 219193_at | 0.2037 | 0.6653 | |
| GSE77861 | WDR70 | 55100 | 219193_at | 0.1513 | 0.5611 | |
| GSE97050 | WDR70 | 55100 | A_23_P30474 | -0.0294 | 0.8915 | |
| SRP007169 | WDR70 | 55100 | RNAseq | 0.2985 | 0.4827 | |
| SRP008496 | WDR70 | 55100 | RNAseq | 0.1858 | 0.5145 | |
| SRP064894 | WDR70 | 55100 | RNAseq | 0.2698 | 0.0642 | |
| SRP133303 | WDR70 | 55100 | RNAseq | 0.0629 | 0.6135 | |
| SRP159526 | WDR70 | 55100 | RNAseq | 0.4720 | 0.0766 | |
| SRP193095 | WDR70 | 55100 | RNAseq | 0.0113 | 0.9067 | |
| SRP219564 | WDR70 | 55100 | RNAseq | -0.0928 | 0.7580 | |
| TCGA | WDR70 | 55100 | RNAseq | 0.1987 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR70 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR70:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR70 | 55100 | 10 | 0 | 20 | |
| GSE20123 | WDR70 | 55100 | 10 | 0 | 20 | |
| GSE43470 | WDR70 | 55100 | 18 | 0 | 25 | |
| GSE46452 | WDR70 | 55100 | 5 | 22 | 32 | |
| GSE47630 | WDR70 | 55100 | 6 | 12 | 22 | |
| GSE54993 | WDR70 | 55100 | 5 | 4 | 61 | |
| GSE54994 | WDR70 | 55100 | 25 | 3 | 25 | |
| GSE60625 | WDR70 | 55100 | 0 | 0 | 11 | |
| GSE74703 | WDR70 | 55100 | 14 | 0 | 22 | |
| GSE74704 | WDR70 | 55100 | 9 | 0 | 11 | |
| TCGA | WDR70 | 55100 | 52 | 7 | 37 |
Total number of gains: 154; Total number of losses: 48; Total Number of normals: 286.
Somatic mutations of WDR70:
Generating mutation plots.
Highly correlated genes for WDR70:
Showing top 20/538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR70 | CBX5 | 0.768837 | 3 | 0 | 3 |
| WDR70 | RNF138 | 0.760951 | 3 | 0 | 3 |
| WDR70 | ZNF234 | 0.757016 | 3 | 0 | 3 |
| WDR70 | KRR1 | 0.747543 | 4 | 0 | 4 |
| WDR70 | MCOLN1 | 0.747534 | 3 | 0 | 3 |
| WDR70 | CCDC14 | 0.739929 | 3 | 0 | 3 |
| WDR70 | USP12 | 0.732304 | 3 | 0 | 3 |
| WDR70 | UTP20 | 0.718247 | 3 | 0 | 3 |
| WDR70 | RBM26 | 0.716091 | 3 | 0 | 3 |
| WDR70 | UBE2L3 | 0.714516 | 3 | 0 | 3 |
| WDR70 | AHCTF1 | 0.711898 | 3 | 0 | 3 |
| WDR70 | ZNF121 | 0.708344 | 4 | 0 | 4 |
| WDR70 | SUMO3 | 0.70424 | 4 | 0 | 4 |
| WDR70 | MMS19 | 0.703195 | 3 | 0 | 3 |
| WDR70 | ZNF75A | 0.692874 | 3 | 0 | 3 |
| WDR70 | PIF1 | 0.68599 | 3 | 0 | 3 |
| WDR70 | XAB2 | 0.683184 | 3 | 0 | 3 |
| WDR70 | CDC26 | 0.682434 | 3 | 0 | 3 |
| WDR70 | VGLL4 | 0.681253 | 3 | 0 | 3 |
| WDR70 | TADA2A | 0.680204 | 4 | 0 | 3 |
For details and further investigation, click here
