| Full name: mitochondrial ribosomal protein S30 | Alias Symbol: PAP | ||
| Type: protein-coding gene | Cytoband: 5p12 | ||
| Entrez ID: 10884 | HGNC ID: HGNC:8769 | Ensembl Gene: ENSG00000112996 | OMIM ID: 611991 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPS30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS30 | 10884 | 218398_at | 0.3382 | 0.2648 | |
| GSE20347 | MRPS30 | 10884 | 218398_at | 0.5654 | 0.0005 | |
| GSE23400 | MRPS30 | 10884 | 218398_at | 0.5272 | 0.0000 | |
| GSE26886 | MRPS30 | 10884 | 218398_at | 0.4302 | 0.0720 | |
| GSE29001 | MRPS30 | 10884 | 218398_at | 0.3541 | 0.3359 | |
| GSE38129 | MRPS30 | 10884 | 218398_at | 0.7351 | 0.0000 | |
| GSE45670 | MRPS30 | 10884 | 218398_at | 0.3256 | 0.1077 | |
| GSE53622 | MRPS30 | 10884 | 78704 | 0.4022 | 0.0000 | |
| GSE53624 | MRPS30 | 10884 | 78704 | 0.6982 | 0.0000 | |
| GSE63941 | MRPS30 | 10884 | 218398_at | 2.0621 | 0.0001 | |
| GSE77861 | MRPS30 | 10884 | 218398_at | 0.5066 | 0.1685 | |
| GSE97050 | MRPS30 | 10884 | A_23_P252362 | 0.2693 | 0.2206 | |
| SRP007169 | MRPS30 | 10884 | RNAseq | 0.8772 | 0.0779 | |
| SRP008496 | MRPS30 | 10884 | RNAseq | 0.7821 | 0.0404 | |
| SRP064894 | MRPS30 | 10884 | RNAseq | 0.2039 | 0.2022 | |
| SRP133303 | MRPS30 | 10884 | RNAseq | 0.1458 | 0.3473 | |
| SRP159526 | MRPS30 | 10884 | RNAseq | 0.6267 | 0.1460 | |
| SRP193095 | MRPS30 | 10884 | RNAseq | 0.0534 | 0.6336 | |
| SRP219564 | MRPS30 | 10884 | RNAseq | 0.1831 | 0.5216 | |
| TCGA | MRPS30 | 10884 | RNAseq | 0.1744 | 0.0032 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPS30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS30 | 10884 | 9 | 1 | 20 | |
| GSE20123 | MRPS30 | 10884 | 9 | 1 | 20 | |
| GSE43470 | MRPS30 | 10884 | 16 | 0 | 27 | |
| GSE46452 | MRPS30 | 10884 | 5 | 22 | 32 | |
| GSE47630 | MRPS30 | 10884 | 6 | 12 | 22 | |
| GSE54993 | MRPS30 | 10884 | 6 | 3 | 61 | |
| GSE54994 | MRPS30 | 10884 | 24 | 2 | 27 | |
| GSE60625 | MRPS30 | 10884 | 0 | 0 | 11 | |
| GSE74703 | MRPS30 | 10884 | 13 | 0 | 23 | |
| GSE74704 | MRPS30 | 10884 | 8 | 1 | 11 | |
| TCGA | MRPS30 | 10884 | 52 | 8 | 36 |
Total number of gains: 148; Total number of losses: 50; Total Number of normals: 290.
Somatic mutations of MRPS30:
Generating mutation plots.
Highly correlated genes for MRPS30:
Showing top 20/1444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS30 | CMTM4 | 0.821568 | 3 | 0 | 3 |
| MRPS30 | GPR160 | 0.813724 | 3 | 0 | 3 |
| MRPS30 | ZNF121 | 0.809179 | 3 | 0 | 3 |
| MRPS30 | SORL1 | 0.808396 | 3 | 0 | 3 |
| MRPS30 | ZNF664 | 0.764939 | 3 | 0 | 3 |
| MRPS30 | UBE2J2 | 0.752907 | 3 | 0 | 3 |
| MRPS30 | ACBD5 | 0.75266 | 3 | 0 | 3 |
| MRPS30 | PRPF38A | 0.743999 | 3 | 0 | 3 |
| MRPS30 | MRPL38 | 0.743887 | 4 | 0 | 4 |
| MRPS30 | ABHD2 | 0.725618 | 3 | 0 | 3 |
| MRPS30 | ZNF131 | 0.722925 | 3 | 0 | 3 |
| MRPS30 | CNOT2 | 0.722458 | 3 | 0 | 3 |
| MRPS30 | INTS10 | 0.722436 | 4 | 0 | 3 |
| MRPS30 | TMTC3 | 0.722428 | 3 | 0 | 3 |
| MRPS30 | BRIX1 | 0.722039 | 13 | 0 | 11 |
| MRPS30 | NFKB2 | 0.717015 | 4 | 0 | 3 |
| MRPS30 | ZNF766 | 0.714305 | 3 | 0 | 3 |
| MRPS30 | KCTD1 | 0.711025 | 3 | 0 | 3 |
| MRPS30 | ZNRD1 | 0.709315 | 4 | 0 | 3 |
| MRPS30 | SMARCAD1 | 0.708728 | 4 | 0 | 3 |
For details and further investigation, click here
