CARD17

 

Full name: caspase recruitment domain family member 17 Alias Symbol: INCA
Type: protein-coding gene Cytoband: 11q22.3
Entrez ID: 440068 HGNC ID: HGNC:33827 Ensembl Gene: ENSG00000255221 OMIM ID: 609490
Drug and gene relationship at DGIdb

 

Expression of CARD17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 CARD17 440068 87135 0.2630 0.0118
GSE53624 CARD17 440068 87135 -0.0622 0.6311
GSE97050 CARD17 440068 A_24_P192805 0.4672 0.3866
SRP159526 CARD17 440068 RNAseq -1.0063 0.2224
TCGA CARD17 440068 RNAseq 3.8647 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by CARD17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CARD17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CARD17 440068 1 11 18
GSE20123 CARD17 440068 1 11 18
GSE43470 CARD17 440068 2 6 35
GSE46452 CARD17 440068 3 26 30
GSE47630 CARD17 440068 2 19 19
GSE54993 CARD17 440068 9 1 60
GSE54994 CARD17 440068 4 19 30
GSE60625 CARD17 440068 0 3 8
GSE74703 CARD17 440068 1 4 31
GSE74704 CARD17 440068 1 7 12
TCGA CARD17 440068 9 44 43

Total number of gains: 33; Total number of losses: 151; Total Number of normals: 304.  

 

Somatic mutations of CARD17:

 

Generating mutation plots.

 

Highly correlated genes for CARD17:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CARD17CARD160.909701303
CARD17CASP10.757745403
CARD17MLKL0.671427303
CARD17SLAMF70.654622303
CARD17CASP40.64086403
CARD17BTN3A20.615788303

For details and further investigation, click here