| Full name: caspase recruitment domain family member 16 | Alias Symbol: COP1|COP|PSEUDO-ICE | ||
| Type: protein-coding gene | Cytoband: 11q22.3 | ||
| Entrez ID: 114769 | HGNC ID: HGNC:33701 | Ensembl Gene: ENSG00000204397 | OMIM ID: 615680 |
| Drug and gene relationship at DGIdb | |||
Expression of CARD16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CARD16 | 114769 | 1552701_a_at | -0.1633 | 0.8474 | |
| GSE26886 | CARD16 | 114769 | 1552701_a_at | 0.2280 | 0.5046 | |
| GSE45670 | CARD16 | 114769 | 1552701_a_at | 0.4377 | 0.0891 | |
| GSE53622 | CARD16 | 114769 | 83560 | 0.2231 | 0.0116 | |
| GSE53624 | CARD16 | 114769 | 83560 | 0.0206 | 0.8548 | |
| GSE63941 | CARD16 | 114769 | 1552701_a_at | -2.6900 | 0.0851 | |
| GSE77861 | CARD16 | 114769 | 1552701_a_at | -0.7093 | 0.1312 | |
| GSE97050 | CARD16 | 114769 | A_23_P64173 | 0.5731 | 0.2452 | |
| SRP007169 | CARD16 | 114769 | RNAseq | 0.4006 | 0.4411 | |
| SRP064894 | CARD16 | 114769 | RNAseq | 0.2783 | 0.2623 | |
| SRP133303 | CARD16 | 114769 | RNAseq | 0.1510 | 0.4318 | |
| SRP159526 | CARD16 | 114769 | RNAseq | -0.0300 | 0.9484 | |
| SRP193095 | CARD16 | 114769 | RNAseq | -0.3680 | 0.0248 | |
| SRP219564 | CARD16 | 114769 | RNAseq | 0.2620 | 0.5548 | |
| TCGA | CARD16 | 114769 | RNAseq | 0.4691 | 0.0041 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CARD16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CARD16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CARD16 | 114769 | 1 | 11 | 18 | |
| GSE20123 | CARD16 | 114769 | 1 | 11 | 18 | |
| GSE43470 | CARD16 | 114769 | 3 | 6 | 34 | |
| GSE46452 | CARD16 | 114769 | 3 | 26 | 30 | |
| GSE47630 | CARD16 | 114769 | 2 | 19 | 19 | |
| GSE54993 | CARD16 | 114769 | 9 | 1 | 60 | |
| GSE54994 | CARD16 | 114769 | 4 | 19 | 30 | |
| GSE60625 | CARD16 | 114769 | 0 | 3 | 8 | |
| GSE74703 | CARD16 | 114769 | 2 | 4 | 30 | |
| GSE74704 | CARD16 | 114769 | 1 | 7 | 12 | |
| TCGA | CARD16 | 114769 | 9 | 44 | 43 |
Total number of gains: 35; Total number of losses: 151; Total Number of normals: 302.
Somatic mutations of CARD16:
Generating mutation plots.
Highly correlated genes for CARD16:
Showing top 20/149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CARD16 | CARD17 | 0.909701 | 3 | 0 | 3 |
| CARD16 | CD2AP | 0.764545 | 3 | 0 | 3 |
| CARD16 | FAM126B | 0.712964 | 3 | 0 | 3 |
| CARD16 | SRD5A1 | 0.710342 | 3 | 0 | 3 |
| CARD16 | HLA-DQB1 | 0.703933 | 3 | 0 | 3 |
| CARD16 | PGM2 | 0.701593 | 3 | 0 | 3 |
| CARD16 | HPSE | 0.699737 | 3 | 0 | 3 |
| CARD16 | TMEM126A | 0.698687 | 3 | 0 | 3 |
| CARD16 | METTL15 | 0.691145 | 3 | 0 | 3 |
| CARD16 | PRKCD | 0.690119 | 3 | 0 | 3 |
| CARD16 | CASP1 | 0.686415 | 9 | 0 | 7 |
| CARD16 | STXBP5 | 0.680613 | 3 | 0 | 3 |
| CARD16 | ZNF680 | 0.67707 | 3 | 0 | 3 |
| CARD16 | ACTR3C | 0.671253 | 3 | 0 | 3 |
| CARD16 | STT3B | 0.666207 | 3 | 0 | 3 |
| CARD16 | CASP4 | 0.660737 | 8 | 0 | 7 |
| CARD16 | UCHL3 | 0.658366 | 4 | 0 | 3 |
| CARD16 | RAB42 | 0.656493 | 4 | 0 | 3 |
| CARD16 | NCK1 | 0.653981 | 4 | 0 | 4 |
| CARD16 | ZSCAN12 | 0.649509 | 3 | 0 | 3 |
For details and further investigation, click here
