CPNE4

 

Full name: copine 4 Alias Symbol: COPN4|CPN4
Type: protein-coding gene Cytoband: 3q22.1
Entrez ID: 131034 HGNC ID: HGNC:2317 Ensembl Gene: ENSG00000196353 OMIM ID: 604208
Drug and gene relationship at DGIdb

 

Expression of CPNE4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CPNE4 131034 228796_at 0.2859 0.4429
GSE26886 CPNE4 131034 228796_at 0.2886 0.1095
GSE45670 CPNE4 131034 228796_at -0.0998 0.4357
GSE53622 CPNE4 131034 70011 -0.5727 0.0019
GSE53624 CPNE4 131034 70011 -0.2695 0.0551
GSE63941 CPNE4 131034 228796_at 0.1939 0.6504
GSE77861 CPNE4 131034 228796_at -0.1929 0.0573
TCGA CPNE4 131034 RNAseq -1.6219 0.0380

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by CPNE4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CPNE4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CPNE4 131034 16 0 14
GSE20123 CPNE4 131034 16 0 14
GSE43470 CPNE4 131034 21 0 22
GSE46452 CPNE4 131034 15 4 40
GSE47630 CPNE4 131034 18 3 19
GSE54993 CPNE4 131034 2 8 60
GSE54994 CPNE4 131034 32 3 18
GSE60625 CPNE4 131034 0 6 5
GSE74703 CPNE4 131034 18 0 18
GSE74704 CPNE4 131034 12 0 8
TCGA CPNE4 131034 59 6 31

Total number of gains: 209; Total number of losses: 30; Total Number of normals: 249.  

 

Somatic mutations of CPNE4:

 

Generating mutation plots.

 

Highly correlated genes for CPNE4:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CPNE4RLN20.642819303
CPNE4RNFT20.629768303
CPNE4SCARNA20.615565303
CPNE4ZNF5720.595794303
CPNE4MUC160.595274403

For details and further investigation, click here