ELFN2

 

Full name: extracellular leucine rich repeat and fibronectin type III domain containing 2 Alias Symbol: dJ63G5.3|KIAA1904
Type: protein-coding gene Cytoband: 22q13.1
Entrez ID: 114794 HGNC ID: HGNC:29396 Ensembl Gene: ENSG00000166897 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ELFN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ELFN2 114794 1560713_a_at -0.1311 0.4893
GSE26886 ELFN2 114794 1561369_at 0.0579 0.6556
GSE45670 ELFN2 114794 1560713_a_at 0.1259 0.1728
GSE53622 ELFN2 114794 33050 0.2071 0.0789
GSE53624 ELFN2 114794 33050 0.0746 0.5353
GSE63941 ELFN2 114794 1559072_a_at 0.7072 0.4639
GSE77861 ELFN2 114794 1561369_at -0.0398 0.7179
SRP159526 ELFN2 114794 RNAseq 2.9474 0.0018
TCGA ELFN2 114794 RNAseq 0.7025 0.1465

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by ELFN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ELFN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ELFN2 114794 6 6 18
GSE20123 ELFN2 114794 6 5 19
GSE43470 ELFN2 114794 4 6 33
GSE46452 ELFN2 114794 32 2 25
GSE47630 ELFN2 114794 9 4 27
GSE54993 ELFN2 114794 3 6 61
GSE54994 ELFN2 114794 9 8 36
GSE60625 ELFN2 114794 5 0 6
GSE74703 ELFN2 114794 4 4 28
GSE74704 ELFN2 114794 3 2 15
TCGA ELFN2 114794 27 16 53

Total number of gains: 108; Total number of losses: 59; Total Number of normals: 321.  

 

Somatic mutations of ELFN2:

 

Generating mutation plots.

 

Highly correlated genes for ELFN2:

 

Showing all 10 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ELFN2FHAD10.647295303
ELFN2PRRX2-AS10.604587303
ELFN2HCP5B0.598787303
ELFN2LINC004100.58536403
ELFN2SSUH20.582614303
ELFN2WWC2-AS20.573383403
ELFN2CDHR20.563014403
ELFN2CSNK1G2-AS10.554841403
ELFN2NCR20.548702303
ELFN2C2orf720.532207403

For details and further investigation, click here