C2orf72

 

Full name: chromosome 2 open reading frame 72 Alias Symbol: LOC257407
Type: protein-coding gene Cytoband: 2q37.1
Entrez ID: 257407 HGNC ID: HGNC:27418 Ensembl Gene: ENSG00000204128 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C2orf72:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C2orf72 257407 1556464_a_at -0.0247 0.9516
GSE20347 C2orf72 257407 213143_at -0.0935 0.2355
GSE23400 C2orf72 257407 213143_at -0.1965 0.0000
GSE26886 C2orf72 257407 1556464_a_at -0.0287 0.8606
GSE29001 C2orf72 257407 213143_at -0.2179 0.2509
GSE38129 C2orf72 257407 213143_at -0.2332 0.0061
GSE45670 C2orf72 257407 1556464_a_at -0.0536 0.5713
GSE53622 C2orf72 257407 10869 0.4170 0.0004
GSE53624 C2orf72 257407 10869 0.2188 0.0303
GSE63941 C2orf72 257407 1556464_a_at 0.2512 0.0436
GSE77861 C2orf72 257407 1556464_a_at -0.1882 0.1701
GSE97050 C2orf72 257407 A_33_P3237207 0.0363 0.8750
SRP159526 C2orf72 257407 RNAseq 1.6702 0.0140
TCGA C2orf72 257407 RNAseq -1.7736 0.0000

Upregulated datasets: 1; Downregulated datasets: 1.  


 

Survival by C2orf72 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C2orf72:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C2orf72 257407 1 13 16
GSE20123 C2orf72 257407 1 12 17
GSE43470 C2orf72 257407 1 8 34
GSE46452 C2orf72 257407 0 5 54
GSE47630 C2orf72 257407 4 5 31
GSE54993 C2orf72 257407 2 2 66
GSE54994 C2orf72 257407 6 11 36
GSE60625 C2orf72 257407 0 3 8
GSE74703 C2orf72 257407 1 6 29
GSE74704 C2orf72 257407 1 5 14
TCGA C2orf72 257407 13 27 56

Total number of gains: 30; Total number of losses: 97; Total Number of normals: 361.  


 

Somatic mutations of C2orf72:

 

Generating mutation plots.

 

Highly correlated genes for C2orf72:

 

Showing top 20/1247 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C2orf72PAX60.839308303
C2orf72OR2T270.825745303
C2orf72STRC0.818919303
C2orf72YY20.814277303
C2orf72C9orf1530.813949303
C2orf72DCDC10.806329303
C2orf72MRGPRG0.789867303
C2orf72PLA2G2C0.78403303
C2orf72OR2T10.769956303
C2orf72BBC30.769409303
C2orf72LHB0.7684303
C2orf72KRTAP10-120.767303
C2orf72OR2A50.765796303
C2orf72LBX20.761921303
C2orf72GPHA20.761207404
C2orf72FAM181A0.760935303
C2orf72C1QL20.760845303
C2orf72MS4A180.760627303
C2orf72LGALS120.757644404
C2orf72C11orf860.75705303

For details and further investigation, click here