| Full name: cadherin related family member 2 | Alias Symbol: PC-LKC|FLJ20124|FLJ20383|PCLKC | ||
| Type: protein-coding gene | Cytoband: 5q35.2 | ||
| Entrez ID: 54825 | HGNC ID: HGNC:18231 | Ensembl Gene: ENSG00000074276 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CDHR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDHR2 | 54825 | 220186_s_at | -0.0863 | 0.6309 | |
| GSE20347 | CDHR2 | 54825 | 220186_s_at | -0.0858 | 0.1894 | |
| GSE23400 | CDHR2 | 54825 | 220186_s_at | -0.0912 | 0.0005 | |
| GSE26886 | CDHR2 | 54825 | 220186_s_at | -0.1133 | 0.2675 | |
| GSE29001 | CDHR2 | 54825 | 220186_s_at | -0.0320 | 0.8330 | |
| GSE38129 | CDHR2 | 54825 | 220186_s_at | -0.1829 | 0.0031 | |
| GSE45670 | CDHR2 | 54825 | 220186_s_at | 0.0644 | 0.3883 | |
| GSE53622 | CDHR2 | 54825 | 57385 | 0.0336 | 0.7027 | |
| GSE53624 | CDHR2 | 54825 | 57385 | -0.1852 | 0.0195 | |
| GSE63941 | CDHR2 | 54825 | 220186_s_at | 0.0583 | 0.6149 | |
| GSE77861 | CDHR2 | 54825 | 220186_s_at | -0.1585 | 0.1266 | |
| GSE97050 | CDHR2 | 54825 | A_23_P133338 | 0.3528 | 0.2839 | |
| SRP133303 | CDHR2 | 54825 | RNAseq | 0.9337 | 0.0003 | |
| TCGA | CDHR2 | 54825 | RNAseq | -3.8530 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CDHR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDHR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDHR2 | 54825 | 2 | 13 | 15 | |
| GSE20123 | CDHR2 | 54825 | 2 | 13 | 15 | |
| GSE43470 | CDHR2 | 54825 | 1 | 11 | 31 | |
| GSE46452 | CDHR2 | 54825 | 0 | 27 | 32 | |
| GSE47630 | CDHR2 | 54825 | 0 | 20 | 20 | |
| GSE54993 | CDHR2 | 54825 | 10 | 2 | 58 | |
| GSE54994 | CDHR2 | 54825 | 2 | 17 | 34 | |
| GSE60625 | CDHR2 | 54825 | 1 | 0 | 10 | |
| GSE74703 | CDHR2 | 54825 | 1 | 7 | 28 | |
| GSE74704 | CDHR2 | 54825 | 1 | 6 | 13 | |
| TCGA | CDHR2 | 54825 | 7 | 35 | 54 |
Total number of gains: 27; Total number of losses: 151; Total Number of normals: 310.
Somatic mutations of CDHR2:
Generating mutation plots.
Highly correlated genes for CDHR2:
Showing top 20/558 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDHR2 | C11orf94 | 0.780694 | 3 | 0 | 3 |
| CDHR2 | CHDH | 0.748876 | 3 | 0 | 3 |
| CDHR2 | KRT35 | 0.743199 | 5 | 0 | 4 |
| CDHR2 | WDR60 | 0.728318 | 3 | 0 | 3 |
| CDHR2 | SPTA1 | 0.720886 | 3 | 0 | 3 |
| CDHR2 | VCX2 | 0.714627 | 3 | 0 | 3 |
| CDHR2 | ZNF219 | 0.711456 | 3 | 0 | 3 |
| CDHR2 | LRFN2 | 0.708271 | 3 | 0 | 3 |
| CDHR2 | DEFB108B | 0.707242 | 3 | 0 | 3 |
| CDHR2 | TLR6 | 0.701542 | 3 | 0 | 3 |
| CDHR2 | RGL4 | 0.701234 | 4 | 0 | 3 |
| CDHR2 | C11orf86 | 0.699446 | 3 | 0 | 3 |
| CDHR2 | TTLL9 | 0.699376 | 4 | 0 | 4 |
| CDHR2 | INCENP | 0.695379 | 3 | 0 | 3 |
| CDHR2 | RSPH4A | 0.687867 | 3 | 0 | 3 |
| CDHR2 | SLC25A18 | 0.686147 | 3 | 0 | 3 |
| CDHR2 | SIX6 | 0.68342 | 4 | 0 | 3 |
| CDHR2 | MS4A3 | 0.677155 | 3 | 0 | 3 |
| CDHR2 | CNPY1 | 0.672849 | 3 | 0 | 3 |
| CDHR2 | IQSEC3 | 0.672588 | 4 | 0 | 3 |
For details and further investigation, click here
