KNDC1

 

Full name: kinase non-catalytic C-lobe domain containing 1 Alias Symbol: KIAA1768|bB439H18.3|FLJ25027|Very-KIND|v-KIND
Type: protein-coding gene Cytoband: 10q26.3
Entrez ID: 85442 HGNC ID: HGNC:29374 Ensembl Gene: ENSG00000171798 OMIM ID: 616237
Drug and gene relationship at DGIdb

 

Expression of KNDC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KNDC1 85442 230359_at -0.1319 0.4791
GSE26886 KNDC1 85442 230359_at 0.1823 0.1315
GSE45670 KNDC1 85442 230558_at 0.2314 0.0048
GSE53622 KNDC1 85442 14646 -0.5430 0.0006
GSE53624 KNDC1 85442 14646 -0.1380 0.1099
GSE63941 KNDC1 85442 230359_at 0.0197 0.9734
GSE77861 KNDC1 85442 230558_at -0.0084 0.9655
SRP064894 KNDC1 85442 RNAseq 0.2533 0.4581
SRP133303 KNDC1 85442 RNAseq 0.1764 0.4645
SRP159526 KNDC1 85442 RNAseq 0.8979 0.2408
SRP193095 KNDC1 85442 RNAseq -0.0522 0.7631
SRP219564 KNDC1 85442 RNAseq -0.3260 0.5095
TCGA KNDC1 85442 RNAseq -0.2562 0.6142

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by KNDC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KNDC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KNDC1 85442 3 8 19
GSE20123 KNDC1 85442 3 9 18
GSE43470 KNDC1 85442 0 9 34
GSE46452 KNDC1 85442 1 11 47
GSE47630 KNDC1 85442 4 13 23
GSE54993 KNDC1 85442 8 2 60
GSE54994 KNDC1 85442 1 9 43
GSE60625 KNDC1 85442 0 0 11
GSE74703 KNDC1 85442 0 6 30
GSE74704 KNDC1 85442 3 4 13
TCGA KNDC1 85442 7 28 61

Total number of gains: 30; Total number of losses: 99; Total Number of normals: 359.  

 

Somatic mutations of KNDC1:

 

Generating mutation plots.

 

Highly correlated genes for KNDC1:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KNDC1NOL30.611058303
KNDC1FRMD10.583269303
KNDC1ARIH2OS0.580608403
KNDC1NRP20.543622303
KNDC1LINC003340.530051403
KNDC1MYL40.503159503

For details and further investigation, click here