| Full name: nucleolar protein 3 | Alias Symbol: ARC|NOP30|MYP|CARD2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 8996 | HGNC ID: HGNC:7869 | Ensembl Gene: | OMIM ID: 605235 |
| Drug and gene relationship at DGIdb | |||
Expression of NOL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOL3 | 8996 | 59625_at | -0.4945 | 0.2838 | |
| GSE20347 | NOL3 | 8996 | 59625_at | 0.0502 | 0.7035 | |
| GSE23400 | NOL3 | 8996 | 221567_at | -0.0035 | 0.9665 | |
| GSE26886 | NOL3 | 8996 | 59625_at | 0.1274 | 0.6619 | |
| GSE29001 | NOL3 | 8996 | 221567_at | -0.2067 | 0.3309 | |
| GSE38129 | NOL3 | 8996 | 59625_at | 0.0604 | 0.6629 | |
| GSE45670 | NOL3 | 8996 | 59625_at | -0.0279 | 0.8891 | |
| GSE63941 | NOL3 | 8996 | 59625_at | 0.2690 | 0.6637 | |
| GSE77861 | NOL3 | 8996 | 59625_at | 0.1232 | 0.6189 | |
| GSE97050 | NOL3 | 8996 | A_23_P206371 | -0.5380 | 0.1236 | |
| SRP007169 | NOL3 | 8996 | RNAseq | -1.3297 | 0.0066 | |
| SRP008496 | NOL3 | 8996 | RNAseq | -1.5292 | 0.0000 | |
| SRP064894 | NOL3 | 8996 | RNAseq | -0.1923 | 0.4639 | |
| SRP133303 | NOL3 | 8996 | RNAseq | -0.4152 | 0.0044 | |
| SRP159526 | NOL3 | 8996 | RNAseq | -0.2791 | 0.4087 | |
| SRP193095 | NOL3 | 8996 | RNAseq | -0.1652 | 0.3643 | |
| SRP219564 | NOL3 | 8996 | RNAseq | -0.4948 | 0.3006 | |
| TCGA | NOL3 | 8996 | RNAseq | 0.0883 | 0.3133 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NOL3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NOL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOL3 | 8996 | 8 | 2 | 20 | |
| GSE20123 | NOL3 | 8996 | 8 | 2 | 20 | |
| GSE43470 | NOL3 | 8996 | 1 | 9 | 33 | |
| GSE46452 | NOL3 | 8996 | 38 | 1 | 20 | |
| GSE47630 | NOL3 | 8996 | 10 | 8 | 22 | |
| GSE54993 | NOL3 | 8996 | 2 | 4 | 64 | |
| GSE54994 | NOL3 | 8996 | 8 | 10 | 35 | |
| GSE60625 | NOL3 | 8996 | 4 | 0 | 7 | |
| GSE74703 | NOL3 | 8996 | 1 | 6 | 29 | |
| GSE74704 | NOL3 | 8996 | 5 | 1 | 14 | |
| TCGA | NOL3 | 8996 | 29 | 12 | 55 |
Total number of gains: 114; Total number of losses: 55; Total Number of normals: 319.
Somatic mutations of NOL3:
Generating mutation plots.
Highly correlated genes for NOL3:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOL3 | AK4 | 0.722959 | 3 | 0 | 3 |
| NOL3 | MAFF | 0.714655 | 3 | 0 | 3 |
| NOL3 | PNRC1 | 0.692844 | 3 | 0 | 3 |
| NOL3 | MRPS21 | 0.671019 | 3 | 0 | 3 |
| NOL3 | MAPK10 | 0.656537 | 3 | 0 | 3 |
| NOL3 | CSRP1 | 0.648976 | 3 | 0 | 3 |
| NOL3 | WLS | 0.642543 | 3 | 0 | 3 |
| NOL3 | FOSL2 | 0.641681 | 3 | 0 | 3 |
| NOL3 | FYCO1 | 0.622755 | 3 | 0 | 3 |
| NOL3 | PITPNB | 0.622381 | 3 | 0 | 3 |
| NOL3 | CST3 | 0.617652 | 3 | 0 | 3 |
| NOL3 | CALY | 0.616742 | 3 | 0 | 3 |
| NOL3 | KNDC1 | 0.611058 | 3 | 0 | 3 |
| NOL3 | ZFP36 | 0.602551 | 3 | 0 | 3 |
| NOL3 | AHNAK | 0.60174 | 3 | 0 | 3 |
| NOL3 | CLTB | 0.601299 | 3 | 0 | 3 |
| NOL3 | RILP | 0.59775 | 3 | 0 | 3 |
| NOL3 | HOXA3 | 0.595939 | 4 | 0 | 3 |
| NOL3 | NDUFS1 | 0.595731 | 3 | 0 | 3 |
| NOL3 | ANO10 | 0.595581 | 3 | 0 | 3 |
For details and further investigation, click here
