| Full name: neuropilin 2 | Alias Symbol: VEGF165R2 | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 8828 | HGNC ID: HGNC:8005 | Ensembl Gene: ENSG00000118257 | OMIM ID: 602070 |
| Drug and gene relationship at DGIdb | |||
Expression of NRP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRP2 | 8828 | 222877_at | -0.4065 | 0.7370 | |
| GSE20347 | NRP2 | 8828 | 210841_s_at | 0.0781 | 0.3837 | |
| GSE23400 | NRP2 | 8828 | 219367_s_at | -0.2089 | 0.0175 | |
| GSE26886 | NRP2 | 8828 | 210841_s_at | 0.5120 | 0.0007 | |
| GSE29001 | NRP2 | 8828 | 219367_s_at | 0.0444 | 0.8291 | |
| GSE38129 | NRP2 | 8828 | 210841_s_at | -0.0393 | 0.6820 | |
| GSE45670 | NRP2 | 8828 | 225566_at | -0.1279 | 0.6995 | |
| GSE53622 | NRP2 | 8828 | 38384 | 0.7367 | 0.0000 | |
| GSE53624 | NRP2 | 8828 | 38384 | 1.1038 | 0.0000 | |
| GSE63941 | NRP2 | 8828 | 225566_at | -1.5128 | 0.0770 | |
| GSE77861 | NRP2 | 8828 | 210841_s_at | 0.1624 | 0.3841 | |
| GSE97050 | NRP2 | 8828 | A_33_P3297415 | -0.1142 | 0.7963 | |
| SRP007169 | NRP2 | 8828 | RNAseq | 3.6665 | 0.0000 | |
| SRP008496 | NRP2 | 8828 | RNAseq | 3.9337 | 0.0000 | |
| SRP064894 | NRP2 | 8828 | RNAseq | 1.0947 | 0.0001 | |
| SRP133303 | NRP2 | 8828 | RNAseq | 1.1929 | 0.0060 | |
| SRP159526 | NRP2 | 8828 | RNAseq | 0.7345 | 0.1096 | |
| SRP193095 | NRP2 | 8828 | RNAseq | 2.1184 | 0.0000 | |
| SRP219564 | NRP2 | 8828 | RNAseq | 0.4140 | 0.6097 | |
| TCGA | NRP2 | 8828 | RNAseq | 0.0016 | 0.9884 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by NRP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRP2 | 8828 | 3 | 5 | 22 | |
| GSE20123 | NRP2 | 8828 | 3 | 5 | 22 | |
| GSE43470 | NRP2 | 8828 | 1 | 4 | 38 | |
| GSE46452 | NRP2 | 8828 | 1 | 4 | 54 | |
| GSE47630 | NRP2 | 8828 | 4 | 5 | 31 | |
| GSE54993 | NRP2 | 8828 | 0 | 3 | 67 | |
| GSE54994 | NRP2 | 8828 | 9 | 9 | 35 | |
| GSE60625 | NRP2 | 8828 | 0 | 3 | 8 | |
| GSE74703 | NRP2 | 8828 | 1 | 3 | 32 | |
| GSE74704 | NRP2 | 8828 | 3 | 2 | 15 | |
| TCGA | NRP2 | 8828 | 15 | 20 | 61 |
Total number of gains: 40; Total number of losses: 63; Total Number of normals: 385.
Somatic mutations of NRP2:
Generating mutation plots.
Highly correlated genes for NRP2:
Showing top 20/824 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRP2 | DAPK3 | 0.734194 | 4 | 0 | 4 |
| NRP2 | NGF | 0.733657 | 3 | 0 | 3 |
| NRP2 | JMY | 0.729318 | 3 | 0 | 3 |
| NRP2 | RNF115 | 0.72864 | 3 | 0 | 3 |
| NRP2 | PAGE1 | 0.717536 | 3 | 0 | 3 |
| NRP2 | C20orf194 | 0.703569 | 3 | 0 | 3 |
| NRP2 | HOXA4 | 0.701245 | 3 | 0 | 3 |
| NRP2 | B4GALNT1 | 0.699516 | 3 | 0 | 3 |
| NRP2 | LENG8 | 0.693846 | 3 | 0 | 3 |
| NRP2 | NR4A1 | 0.693573 | 5 | 0 | 5 |
| NRP2 | SARDH | 0.693521 | 3 | 0 | 3 |
| NRP2 | MSANTD4 | 0.693125 | 3 | 0 | 3 |
| NRP2 | INE1 | 0.69106 | 3 | 0 | 3 |
| NRP2 | LNP1 | 0.689171 | 3 | 0 | 3 |
| NRP2 | NAP1L5 | 0.688845 | 3 | 0 | 3 |
| NRP2 | FKBP7 | 0.685452 | 5 | 0 | 5 |
| NRP2 | DLGAP4 | 0.685116 | 3 | 0 | 3 |
| NRP2 | ARMC9 | 0.681491 | 5 | 0 | 4 |
| NRP2 | ZHX3 | 0.681349 | 4 | 0 | 3 |
| NRP2 | GRM7 | 0.67902 | 3 | 0 | 3 |
For details and further investigation, click here
