| Full name: FERM domain containing 1 | Alias Symbol: FLJ00181|DKFZp434O0117|FLJ40260|FLJ22615|bA164L23.1 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 79981 | HGNC ID: HGNC:21240 | Ensembl Gene: ENSG00000153303 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
FRMD1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04390 | Hippo signaling pathway |
Expression of FRMD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRMD1 | 79981 | 220819_at | -0.0826 | 0.6496 | |
| GSE20347 | FRMD1 | 79981 | 220819_at | 0.0224 | 0.8074 | |
| GSE23400 | FRMD1 | 79981 | 220819_at | -0.1305 | 0.0004 | |
| GSE26886 | FRMD1 | 79981 | 220819_at | 0.1246 | 0.1684 | |
| GSE29001 | FRMD1 | 79981 | 220819_at | -0.1243 | 0.3896 | |
| GSE38129 | FRMD1 | 79981 | 220819_at | -0.0563 | 0.4766 | |
| GSE45670 | FRMD1 | 79981 | 220819_at | 0.0818 | 0.2603 | |
| GSE63941 | FRMD1 | 79981 | 220819_at | 0.2169 | 0.0432 | |
| GSE77861 | FRMD1 | 79981 | 220819_at | -0.0918 | 0.2786 | |
| GSE97050 | FRMD1 | 79981 | A_23_P81717 | -0.2060 | 0.3814 | |
| TCGA | FRMD1 | 79981 | RNAseq | -3.9516 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FRMD1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FRMD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRMD1 | 79981 | 3 | 6 | 21 | |
| GSE20123 | FRMD1 | 79981 | 2 | 6 | 22 | |
| GSE43470 | FRMD1 | 79981 | 3 | 0 | 40 | |
| GSE46452 | FRMD1 | 79981 | 3 | 10 | 46 | |
| GSE47630 | FRMD1 | 79981 | 7 | 7 | 26 | |
| GSE54993 | FRMD1 | 79981 | 4 | 3 | 63 | |
| GSE54994 | FRMD1 | 79981 | 10 | 8 | 35 | |
| GSE60625 | FRMD1 | 79981 | 1 | 1 | 9 | |
| GSE74703 | FRMD1 | 79981 | 3 | 0 | 33 | |
| GSE74704 | FRMD1 | 79981 | 1 | 3 | 16 | |
| TCGA | FRMD1 | 79981 | 14 | 20 | 62 |
Total number of gains: 51; Total number of losses: 64; Total Number of normals: 373.
Somatic mutations of FRMD1:
Generating mutation plots.
Highly correlated genes for FRMD1:
Showing top 20/1040 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRMD1 | CLEC4G | 0.743129 | 3 | 0 | 3 |
| FRMD1 | GJD4 | 0.72553 | 4 | 0 | 4 |
| FRMD1 | LMF1 | 0.722396 | 4 | 0 | 4 |
| FRMD1 | PHF21B | 0.717705 | 3 | 0 | 3 |
| FRMD1 | LCN8 | 0.715109 | 3 | 0 | 3 |
| FRMD1 | RIIAD1 | 0.713544 | 3 | 0 | 3 |
| FRMD1 | GPR88 | 0.700753 | 3 | 0 | 3 |
| FRMD1 | FMNL1 | 0.699689 | 3 | 0 | 3 |
| FRMD1 | SLC18A3 | 0.698679 | 4 | 0 | 3 |
| FRMD1 | IFNA21 | 0.694795 | 5 | 0 | 5 |
| FRMD1 | SCGN | 0.693049 | 5 | 0 | 4 |
| FRMD1 | ANKDD1A | 0.69064 | 3 | 0 | 3 |
| FRMD1 | IFNA17 | 0.690564 | 4 | 0 | 4 |
| FRMD1 | SYCE3 | 0.689301 | 3 | 0 | 3 |
| FRMD1 | LACRT | 0.688539 | 4 | 0 | 3 |
| FRMD1 | OR4D2 | 0.688483 | 4 | 0 | 3 |
| FRMD1 | SP7 | 0.68747 | 4 | 0 | 3 |
| FRMD1 | SRPK3 | 0.68638 | 5 | 0 | 4 |
| FRMD1 | HRC | 0.686249 | 6 | 0 | 5 |
| FRMD1 | ANKRD33B | 0.685699 | 3 | 0 | 3 |
For details and further investigation, click here
