Full name: low density lipoprotein receptor class A domain containing 1 | Alias Symbol: | ||
Type: protein-coding gene | Cytoband: 1p32.3 | ||
Entrez ID: 388633 | HGNC ID: HGNC:32069 | Ensembl Gene: ENSG00000203985 | OMIM ID: |
Drug and gene relationship at DGIdb |
Expression of LDLRAD1:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE53622 | LDLRAD1 | 388633 | 127695 | -0.4858 | 0.0003 | |
GSE53624 | LDLRAD1 | 388633 | 127695 | -0.7890 | 0.0000 | |
GSE97050 | LDLRAD1 | 388633 | A_24_P491397 | -0.0039 | 0.9878 | |
SRP133303 | LDLRAD1 | 388633 | RNAseq | -0.1788 | 0.7305 | |
SRP159526 | LDLRAD1 | 388633 | RNAseq | -0.8309 | 0.2274 | |
SRP193095 | LDLRAD1 | 388633 | RNAseq | 0.1221 | 0.5119 | |
TCGA | LDLRAD1 | 388633 | RNAseq | 0.3467 | 0.7901 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LDLRAD1 expression:
Note: Click image to view full size file.
Copy number change of LDLRAD1:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | LDLRAD1 | 388633 | 3 | 4 | 23 | |
GSE20123 | LDLRAD1 | 388633 | 3 | 3 | 24 | |
GSE43470 | LDLRAD1 | 388633 | 6 | 2 | 35 | |
GSE46452 | LDLRAD1 | 388633 | 2 | 1 | 56 | |
GSE47630 | LDLRAD1 | 388633 | 8 | 4 | 28 | |
GSE54993 | LDLRAD1 | 388633 | 0 | 0 | 70 | |
GSE54994 | LDLRAD1 | 388633 | 10 | 2 | 41 | |
GSE60625 | LDLRAD1 | 388633 | 0 | 0 | 11 | |
GSE74703 | LDLRAD1 | 388633 | 4 | 1 | 31 | |
GSE74704 | LDLRAD1 | 388633 | 2 | 0 | 18 | |
TCGA | LDLRAD1 | 388633 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 35; Total Number of normals: 405.
Somatic mutations of LDLRAD1:
Generating mutation plots.
Highly correlated genes for LDLRAD1:
Showing all 4 correlated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
LDLRAD1 | CLDN24 | 0.660347 | 3 | 0 | 3 |
LDLRAD1 | RASGEF1C | 0.655159 | 3 | 0 | 3 |
LDLRAD1 | AQP5 | 0.643668 | 3 | 0 | 3 |
LDLRAD1 | CRTC1 | 0.536795 | 3 | 0 | 3 |
For details and further investigation, click here