| Full name: claudin 24 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 100132463 | HGNC ID: HGNC:37200 | Ensembl Gene: ENSG00000185758 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
CLDN24 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of CLDN24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CLDN24 | 100132463 | 159037 | -0.8137 | 0.0000 | |
| GSE53624 | CLDN24 | 100132463 | 159037 | -0.9500 | 0.0000 | |
| GSE97050 | CLDN24 | 100132463 | A_33_P3218089 | -0.1435 | 0.7194 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLDN24 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CLDN24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLDN24 | 100132463 | 2 | 11 | 17 | |
| GSE20123 | CLDN24 | 100132463 | 2 | 11 | 17 | |
| GSE43470 | CLDN24 | 100132463 | 0 | 12 | 31 | |
| GSE46452 | CLDN24 | 100132463 | 1 | 36 | 22 | |
| GSE47630 | CLDN24 | 100132463 | 0 | 22 | 18 | |
| GSE54993 | CLDN24 | 100132463 | 10 | 0 | 60 | |
| GSE54994 | CLDN24 | 100132463 | 2 | 12 | 39 | |
| GSE60625 | CLDN24 | 100132463 | 0 | 0 | 11 | |
| GSE74703 | CLDN24 | 100132463 | 0 | 9 | 27 | |
| GSE74704 | CLDN24 | 100132463 | 1 | 5 | 14 | |
| TCGA | CLDN24 | 100132463 | 11 | 32 | 53 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of CLDN24:
Generating mutation plots.
Highly correlated genes for CLDN24:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLDN24 | OR2Z1 | 0.849989 | 3 | 0 | 3 |
| CLDN24 | GALNT9 | 0.825594 | 3 | 0 | 3 |
| CLDN24 | OR10G8 | 0.810395 | 3 | 0 | 3 |
| CLDN24 | KRTAP20-1 | 0.806203 | 3 | 0 | 3 |
| CLDN24 | SCARA5 | 0.799949 | 3 | 0 | 3 |
| CLDN24 | RRP1 | 0.797387 | 3 | 0 | 3 |
| CLDN24 | PKD2L1 | 0.797246 | 3 | 0 | 3 |
| CLDN24 | MFSD2B | 0.789509 | 3 | 0 | 3 |
| CLDN24 | C14orf180 | 0.787422 | 3 | 0 | 3 |
| CLDN24 | AQP5 | 0.783936 | 3 | 0 | 3 |
| CLDN24 | HTR3A | 0.780703 | 3 | 0 | 3 |
| CLDN24 | TMEM125 | 0.776578 | 3 | 0 | 3 |
| CLDN24 | PHF21B | 0.776016 | 3 | 0 | 3 |
| CLDN24 | UPB1 | 0.773698 | 3 | 0 | 3 |
| CLDN24 | GPT | 0.768518 | 3 | 0 | 3 |
| CLDN24 | RNF151 | 0.767717 | 3 | 0 | 3 |
| CLDN24 | CSTL1 | 0.765502 | 3 | 0 | 3 |
| CLDN24 | SLC2A8 | 0.764657 | 3 | 0 | 3 |
| CLDN24 | ENTPD8 | 0.764143 | 3 | 0 | 3 |
| CLDN24 | OTOF | 0.759687 | 3 | 0 | 3 |
For details and further investigation, click here
