LRRC38

 

Full name: leucine rich repeat containing 38 Alias Symbol: 
Type: protein-coding gene Cytoband: 1p36.21
Entrez ID: 126755 HGNC ID: HGNC:27005 Ensembl Gene: ENSG00000162494 OMIM ID: 615212

 

Expression of LRRC38:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRC38 126755 1558375_at 0.0012 0.9966
GSE26886 LRRC38 126755 1558375_at -0.0319 0.7498
GSE45670 LRRC38 126755 1558375_at 0.0776 0.2603
GSE53622 LRRC38 126755 37140 0.1947 0.1858
GSE53624 LRRC38 126755 37140 0.7348 0.0000
GSE63941 LRRC38 126755 1558375_at 0.0864 0.4502
GSE77861 LRRC38 126755 1558375_at -0.1222 0.1070
SRP133303 LRRC38 126755 RNAseq 0.7839 0.0275
SRP159526 LRRC38 126755 RNAseq 2.6076 0.0043

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by LRRC38 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of LRRC38:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRC38 126755 0 4 26
GSE20123 LRRC38 126755 0 3 27
GSE43470 LRRC38 126755 2 8 33
GSE46452 LRRC38 126755 7 1 51
GSE47630 LRRC38 126755 8 3 29
GSE54993 LRRC38 126755 3 1 66
GSE54994 LRRC38 126755 11 4 38
GSE60625 LRRC38 126755 0 0 11
GSE74703 LRRC38 126755 2 5 29
GSE74704 LRRC38 126755 0 0 20
TCGA LRRC38 126755 10 22 64

Total number of gains: 43; Total number of losses: 51; Total Number of normals: 394.  

 

Somatic mutations of LRRC38:

 

Generating mutation plots.

 

Highly correlated genes for LRRC38:

 

Showing all 4 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRC38WFDC80.591304303
LRRC38SEZ60.581681303
LRRC38IFNK0.541472303
LRRC38PSG60.529574403

For details and further investigation, click here