| Full name: WAP four-disulfide core domain 8 | Alias Symbol: dJ461P17.1|WAP8 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 90199 | HGNC ID: HGNC:16163 | Ensembl Gene: ENSG00000158901 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WFDC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WFDC8 | 90199 | 1554157_a_at | -0.0642 | 0.8337 | |
| GSE20347 | WFDC8 | 90199 | 215276_at | 0.0026 | 0.9744 | |
| GSE23400 | WFDC8 | 90199 | 215276_at | -0.0843 | 0.0026 | |
| GSE26886 | WFDC8 | 90199 | 215276_at | -0.1055 | 0.3392 | |
| GSE29001 | WFDC8 | 90199 | 215276_at | -0.0260 | 0.8701 | |
| GSE38129 | WFDC8 | 90199 | 215276_at | -0.0845 | 0.1757 | |
| GSE45670 | WFDC8 | 90199 | 215276_at | -0.0609 | 0.4063 | |
| GSE53622 | WFDC8 | 90199 | 23106 | 0.1599 | 0.0950 | |
| GSE53624 | WFDC8 | 90199 | 23106 | 0.2346 | 0.0864 | |
| GSE63941 | WFDC8 | 90199 | 215276_at | 0.0987 | 0.4692 | |
| GSE77861 | WFDC8 | 90199 | 215276_at | -0.0872 | 0.3587 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WFDC8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WFDC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WFDC8 | 90199 | 14 | 1 | 15 | |
| GSE20123 | WFDC8 | 90199 | 14 | 1 | 15 | |
| GSE43470 | WFDC8 | 90199 | 12 | 1 | 30 | |
| GSE46452 | WFDC8 | 90199 | 29 | 0 | 30 | |
| GSE47630 | WFDC8 | 90199 | 24 | 1 | 15 | |
| GSE54993 | WFDC8 | 90199 | 0 | 17 | 53 | |
| GSE54994 | WFDC8 | 90199 | 25 | 0 | 28 | |
| GSE60625 | WFDC8 | 90199 | 0 | 0 | 11 | |
| GSE74703 | WFDC8 | 90199 | 10 | 1 | 25 | |
| GSE74704 | WFDC8 | 90199 | 10 | 0 | 10 | |
| TCGA | WFDC8 | 90199 | 45 | 3 | 48 |
Total number of gains: 183; Total number of losses: 25; Total Number of normals: 280.
Somatic mutations of WFDC8:
Generating mutation plots.
Highly correlated genes for WFDC8:
Showing top 20/799 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WFDC8 | CCDC63 | 0.677148 | 3 | 0 | 3 |
| WFDC8 | HCN1 | 0.67614 | 3 | 0 | 3 |
| WFDC8 | HTR1A | 0.667865 | 5 | 0 | 4 |
| WFDC8 | SPACA3 | 0.659862 | 4 | 0 | 3 |
| WFDC8 | MOG | 0.658193 | 5 | 0 | 5 |
| WFDC8 | LINC00544 | 0.655621 | 3 | 0 | 3 |
| WFDC8 | LACRT | 0.654233 | 5 | 0 | 4 |
| WFDC8 | C20orf85 | 0.651998 | 4 | 0 | 4 |
| WFDC8 | C9orf50 | 0.650801 | 3 | 0 | 3 |
| WFDC8 | PRR29 | 0.640448 | 4 | 0 | 4 |
| WFDC8 | FCHO1 | 0.637392 | 4 | 0 | 3 |
| WFDC8 | MUC17 | 0.634821 | 3 | 0 | 3 |
| WFDC8 | LILRA4 | 0.633295 | 6 | 0 | 5 |
| WFDC8 | ASMT | 0.633228 | 5 | 0 | 4 |
| WFDC8 | CST8 | 0.631992 | 8 | 0 | 8 |
| WFDC8 | DSPP | 0.631327 | 3 | 0 | 3 |
| WFDC8 | PROZ | 0.630579 | 5 | 0 | 4 |
| WFDC8 | ZGLP1 | 0.629187 | 5 | 0 | 5 |
| WFDC8 | KSR1 | 0.627989 | 4 | 0 | 3 |
| WFDC8 | MAPK11 | 0.626899 | 3 | 0 | 3 |
For details and further investigation, click here
