| Full name: interferon kappa | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p21.2 | ||
| Entrez ID: 56832 | HGNC ID: HGNC:21714 | Ensembl Gene: ENSG00000147896 | OMIM ID: 615326 |
| Drug and gene relationship at DGIdb | |||
IFNK involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of IFNK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNK | 56832 | 224093_at | -0.1837 | 0.3970 | |
| GSE26886 | IFNK | 56832 | 224093_at | -0.0526 | 0.6121 | |
| GSE45670 | IFNK | 56832 | 224093_at | 0.1554 | 0.5316 | |
| GSE53622 | IFNK | 56832 | 127383 | -0.0837 | 0.6102 | |
| GSE53624 | IFNK | 56832 | 127383 | 0.7412 | 0.0000 | |
| GSE63941 | IFNK | 56832 | 224093_at | -0.0430 | 0.7492 | |
| GSE77861 | IFNK | 56832 | 224093_at | -0.1890 | 0.1023 | |
| GSE97050 | IFNK | 56832 | A_23_P310372 | 0.3235 | 0.5367 | |
| SRP133303 | IFNK | 56832 | RNAseq | 0.0386 | 0.8758 | |
| SRP193095 | IFNK | 56832 | RNAseq | -0.2395 | 0.3569 | |
| TCGA | IFNK | 56832 | RNAseq | 1.9514 | 0.1088 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFNK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNK | 56832 | 2 | 14 | 14 | |
| GSE20123 | IFNK | 56832 | 2 | 14 | 14 | |
| GSE43470 | IFNK | 56832 | 1 | 11 | 31 | |
| GSE46452 | IFNK | 56832 | 6 | 18 | 35 | |
| GSE47630 | IFNK | 56832 | 1 | 22 | 17 | |
| GSE54993 | IFNK | 56832 | 7 | 0 | 63 | |
| GSE54994 | IFNK | 56832 | 7 | 14 | 32 | |
| GSE60625 | IFNK | 56832 | 0 | 0 | 11 | |
| GSE74703 | IFNK | 56832 | 1 | 8 | 27 | |
| GSE74704 | IFNK | 56832 | 0 | 11 | 9 | |
| TCGA | IFNK | 56832 | 15 | 46 | 35 |
Total number of gains: 42; Total number of losses: 158; Total Number of normals: 288.
Somatic mutations of IFNK:
Generating mutation plots.
Highly correlated genes for IFNK:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNK | CXCR3 | 0.728021 | 3 | 0 | 3 |
| IFNK | PRRG3 | 0.697587 | 3 | 0 | 3 |
| IFNK | GBP4 | 0.649028 | 3 | 0 | 3 |
| IFNK | SPATA3 | 0.629404 | 3 | 0 | 3 |
| IFNK | LGALS2 | 0.620278 | 3 | 0 | 3 |
| IFNK | TMEM176B | 0.617313 | 3 | 0 | 3 |
| IFNK | LILRA4 | 0.609368 | 4 | 0 | 3 |
| IFNK | SIGLEC1 | 0.603969 | 5 | 0 | 4 |
| IFNK | GLI4 | 0.591204 | 4 | 0 | 3 |
| IFNK | GHRH | 0.559741 | 3 | 0 | 3 |
| IFNK | ONECUT3 | 0.543236 | 3 | 0 | 3 |
| IFNK | LRRC38 | 0.541472 | 3 | 0 | 3 |
| IFNK | C2orf50 | 0.541376 | 3 | 0 | 3 |
| IFNK | GNG5 | 0.536901 | 3 | 0 | 3 |
| IFNK | MROH2B | 0.513807 | 4 | 0 | 3 |
| IFNK | KCTD4 | 0.504927 | 4 | 0 | 3 |
For details and further investigation, click here
