MBD3L1

 

Full name: methyl-CpG binding domain protein 3 like 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 85509 HGNC ID: HGNC:15774 Ensembl Gene: ENSG00000170948 OMIM ID: 607963
Drug and gene relationship at DGIdb

 

Expression of MBD3L1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MBD3L1 85509 1552459_a_at 0.0049 0.9859
GSE26886 MBD3L1 85509 1552459_a_at 0.1985 0.0427
GSE45670 MBD3L1 85509 1552459_a_at 0.1108 0.1629
GSE53622 MBD3L1 85509 7509 -0.0759 0.5247
GSE53624 MBD3L1 85509 7509 -0.0781 0.3307
GSE63941 MBD3L1 85509 1552459_a_at 0.0734 0.7232
GSE77861 MBD3L1 85509 1552459_a_at -0.1474 0.1845

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MBD3L1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MBD3L1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MBD3L1 85509 4 3 23
GSE20123 MBD3L1 85509 3 2 25
GSE43470 MBD3L1 85509 2 5 36
GSE46452 MBD3L1 85509 47 1 11
GSE47630 MBD3L1 85509 5 7 28
GSE54993 MBD3L1 85509 16 2 52
GSE54994 MBD3L1 85509 6 14 33
GSE60625 MBD3L1 85509 9 0 2
GSE74703 MBD3L1 85509 2 4 30
GSE74704 MBD3L1 85509 0 2 18
TCGA MBD3L1 85509 10 19 67

Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.  

 

Somatic mutations of MBD3L1:

 

Generating mutation plots.

 

Highly correlated genes for MBD3L1:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MBD3L1FAM228A0.6152303
MBD3L1SPACA10.598634303
MBD3L1TMEM108-AS10.558852303
MBD3L1XAGE30.53908403
MBD3L1HCCS0.532136403
MBD3L1DNMT3L0.514971503

For details and further investigation, click here