| Full name: major facilitator superfamily domain containing 8 | Alias Symbol: MGC33302 | ||
| Type: protein-coding gene | Cytoband: 4q28.2 | ||
| Entrez ID: 256471 | HGNC ID: HGNC:28486 | Ensembl Gene: ENSG00000164073 | OMIM ID: 611124 |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD8 | 256471 | 229509_at | -0.1409 | 0.7268 | |
| GSE26886 | MFSD8 | 256471 | 229509_at | -0.4854 | 0.0431 | |
| GSE45670 | MFSD8 | 256471 | 229509_at | -0.0304 | 0.8206 | |
| GSE53622 | MFSD8 | 256471 | 11492 | -0.4251 | 0.0000 | |
| GSE53624 | MFSD8 | 256471 | 93757 | -0.2320 | 0.0007 | |
| GSE63941 | MFSD8 | 256471 | 229509_at | -0.1800 | 0.6839 | |
| GSE77861 | MFSD8 | 256471 | 229509_at | 0.0018 | 0.9930 | |
| GSE97050 | MFSD8 | 256471 | A_23_P30162 | 0.0826 | 0.7898 | |
| SRP007169 | MFSD8 | 256471 | RNAseq | 0.2989 | 0.4459 | |
| SRP008496 | MFSD8 | 256471 | RNAseq | 0.3081 | 0.2689 | |
| SRP064894 | MFSD8 | 256471 | RNAseq | -0.3293 | 0.0655 | |
| SRP133303 | MFSD8 | 256471 | RNAseq | 0.0390 | 0.7770 | |
| SRP159526 | MFSD8 | 256471 | RNAseq | -0.3805 | 0.1236 | |
| SRP193095 | MFSD8 | 256471 | RNAseq | -0.4241 | 0.0000 | |
| SRP219564 | MFSD8 | 256471 | RNAseq | -0.2216 | 0.5186 | |
| TCGA | MFSD8 | 256471 | RNAseq | -0.1834 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MFSD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD8 | 256471 | 0 | 12 | 18 | |
| GSE20123 | MFSD8 | 256471 | 0 | 12 | 18 | |
| GSE43470 | MFSD8 | 256471 | 0 | 13 | 30 | |
| GSE46452 | MFSD8 | 256471 | 1 | 36 | 22 | |
| GSE47630 | MFSD8 | 256471 | 0 | 22 | 18 | |
| GSE54993 | MFSD8 | 256471 | 9 | 0 | 61 | |
| GSE54994 | MFSD8 | 256471 | 1 | 11 | 41 | |
| GSE60625 | MFSD8 | 256471 | 0 | 1 | 10 | |
| GSE74703 | MFSD8 | 256471 | 0 | 11 | 25 | |
| GSE74704 | MFSD8 | 256471 | 0 | 6 | 14 | |
| TCGA | MFSD8 | 256471 | 8 | 36 | 52 |
Total number of gains: 19; Total number of losses: 160; Total Number of normals: 309.
Somatic mutations of MFSD8:
Generating mutation plots.
Highly correlated genes for MFSD8:
Showing all 5 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD8 | CEP135 | 0.593532 | 3 | 0 | 3 |
| MFSD8 | CYP2J2 | 0.567098 | 3 | 0 | 3 |
| MFSD8 | RABGGTB | 0.56623 | 4 | 0 | 3 |
| MFSD8 | DNASE1 | 0.553447 | 3 | 0 | 3 |
| MFSD8 | RANBP2 | 0.544198 | 5 | 0 | 4 |
For details and further investigation, click here
