| Full name: centrosomal protein 135 | Alias Symbol: FLJ13621 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 9662 | HGNC ID: HGNC:29086 | Ensembl Gene: ENSG00000174799 | OMIM ID: 611423 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CEP135:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEP135 | 9662 | 206003_at | 0.5851 | 0.1253 | |
| GSE20347 | CEP135 | 9662 | 206003_at | 0.1878 | 0.0963 | |
| GSE23400 | CEP135 | 9662 | 206003_at | 0.3662 | 0.0000 | |
| GSE26886 | CEP135 | 9662 | 206003_at | -0.4392 | 0.1313 | |
| GSE29001 | CEP135 | 9662 | 206003_at | 0.7414 | 0.0526 | |
| GSE38129 | CEP135 | 9662 | 206003_at | 0.4424 | 0.0141 | |
| GSE45670 | CEP135 | 9662 | 206003_at | 0.5554 | 0.0495 | |
| GSE53622 | CEP135 | 9662 | 18307 | 0.3738 | 0.0000 | |
| GSE53624 | CEP135 | 9662 | 18307 | 0.4421 | 0.0000 | |
| GSE63941 | CEP135 | 9662 | 206003_at | -0.8536 | 0.1446 | |
| GSE77861 | CEP135 | 9662 | 206003_at | -0.0688 | 0.6875 | |
| GSE97050 | CEP135 | 9662 | A_23_P212792 | 0.3411 | 0.1832 | |
| SRP007169 | CEP135 | 9662 | RNAseq | -0.1228 | 0.8291 | |
| SRP008496 | CEP135 | 9662 | RNAseq | -0.1704 | 0.6090 | |
| SRP064894 | CEP135 | 9662 | RNAseq | 0.3750 | 0.1884 | |
| SRP133303 | CEP135 | 9662 | RNAseq | 0.7854 | 0.0000 | |
| SRP159526 | CEP135 | 9662 | RNAseq | 0.4525 | 0.2458 | |
| SRP193095 | CEP135 | 9662 | RNAseq | 0.3787 | 0.0001 | |
| SRP219564 | CEP135 | 9662 | RNAseq | 0.3085 | 0.4889 | |
| TCGA | CEP135 | 9662 | RNAseq | 0.3767 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CEP135 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEP135:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEP135 | 9662 | 3 | 11 | 16 | |
| GSE20123 | CEP135 | 9662 | 2 | 11 | 17 | |
| GSE43470 | CEP135 | 9662 | 0 | 14 | 29 | |
| GSE46452 | CEP135 | 9662 | 1 | 36 | 22 | |
| GSE47630 | CEP135 | 9662 | 1 | 18 | 21 | |
| GSE54993 | CEP135 | 9662 | 7 | 0 | 63 | |
| GSE54994 | CEP135 | 9662 | 2 | 10 | 41 | |
| GSE60625 | CEP135 | 9662 | 0 | 0 | 11 | |
| GSE74703 | CEP135 | 9662 | 0 | 12 | 24 | |
| GSE74704 | CEP135 | 9662 | 1 | 6 | 13 | |
| TCGA | CEP135 | 9662 | 19 | 27 | 50 |
Total number of gains: 36; Total number of losses: 145; Total Number of normals: 307.
Somatic mutations of CEP135:
Generating mutation plots.
Highly correlated genes for CEP135:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEP135 | IL23A | 0.733379 | 3 | 0 | 3 |
| CEP135 | TSPAN13 | 0.723034 | 3 | 0 | 3 |
| CEP135 | RPIA | 0.707142 | 3 | 0 | 3 |
| CEP135 | LCORL | 0.703532 | 3 | 0 | 3 |
| CEP135 | TRAIP | 0.653218 | 4 | 0 | 3 |
| CEP135 | CDCA5 | 0.643104 | 5 | 0 | 3 |
| CEP135 | MOB1B | 0.633872 | 4 | 0 | 4 |
| CEP135 | TTC30A | 0.61862 | 4 | 0 | 3 |
| CEP135 | SFT2D1 | 0.608148 | 4 | 0 | 3 |
| CEP135 | RECQL4 | 0.604838 | 5 | 0 | 4 |
| CEP135 | ARHGAP22 | 0.595163 | 4 | 0 | 3 |
| CEP135 | SHQ1 | 0.593698 | 5 | 0 | 3 |
| CEP135 | MFSD8 | 0.593532 | 3 | 0 | 3 |
| CEP135 | RELB | 0.59287 | 8 | 0 | 5 |
| CEP135 | CDC25C | 0.589326 | 5 | 0 | 5 |
| CEP135 | DIAPH3 | 0.589186 | 7 | 0 | 4 |
| CEP135 | NUP160 | 0.588955 | 4 | 0 | 3 |
| CEP135 | ZBTB46 | 0.585973 | 5 | 0 | 3 |
| CEP135 | QPRT | 0.583737 | 5 | 0 | 3 |
| CEP135 | TTC9C | 0.580561 | 5 | 0 | 4 |
For details and further investigation, click here
