| Full name: Rab geranylgeranyltransferase subunit beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 5876 | HGNC ID: HGNC:9796 | Ensembl Gene: ENSG00000137955 | OMIM ID: 179080 |
| Drug and gene relationship at DGIdb | |||
Expression of RABGGTB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RABGGTB | 5876 | 209180_at | -0.0305 | 0.9468 | |
| GSE20347 | RABGGTB | 5876 | 209180_at | 0.0327 | 0.8374 | |
| GSE23400 | RABGGTB | 5876 | 209180_at | 0.1810 | 0.0071 | |
| GSE26886 | RABGGTB | 5876 | 209180_at | -0.9839 | 0.0008 | |
| GSE29001 | RABGGTB | 5876 | 209180_at | 0.1330 | 0.7563 | |
| GSE38129 | RABGGTB | 5876 | 209180_at | 0.2817 | 0.0222 | |
| GSE45670 | RABGGTB | 5876 | 209180_at | 0.1678 | 0.1631 | |
| GSE53622 | RABGGTB | 5876 | 3633 | -0.0001 | 0.9993 | |
| GSE53624 | RABGGTB | 5876 | 3633 | 0.2166 | 0.0121 | |
| GSE63941 | RABGGTB | 5876 | 209180_at | 0.4440 | 0.5458 | |
| GSE77861 | RABGGTB | 5876 | 209180_at | -0.1576 | 0.7180 | |
| GSE97050 | RABGGTB | 5876 | A_24_P336705 | 0.0706 | 0.9402 | |
| SRP007169 | RABGGTB | 5876 | RNAseq | -0.2777 | 0.5361 | |
| SRP008496 | RABGGTB | 5876 | RNAseq | -0.3010 | 0.2009 | |
| SRP064894 | RABGGTB | 5876 | RNAseq | 0.0066 | 0.9647 | |
| SRP133303 | RABGGTB | 5876 | RNAseq | 0.1156 | 0.3671 | |
| SRP159526 | RABGGTB | 5876 | RNAseq | -0.5583 | 0.0405 | |
| SRP193095 | RABGGTB | 5876 | RNAseq | -0.2991 | 0.0030 | |
| SRP219564 | RABGGTB | 5876 | RNAseq | 0.8411 | 0.0732 | |
| TCGA | RABGGTB | 5876 | RNAseq | 0.0070 | 0.8962 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RABGGTB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RABGGTB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RABGGTB | 5876 | 0 | 7 | 23 | |
| GSE20123 | RABGGTB | 5876 | 1 | 7 | 22 | |
| GSE43470 | RABGGTB | 5876 | 3 | 4 | 36 | |
| GSE46452 | RABGGTB | 5876 | 0 | 1 | 58 | |
| GSE47630 | RABGGTB | 5876 | 8 | 6 | 26 | |
| GSE54993 | RABGGTB | 5876 | 0 | 0 | 70 | |
| GSE54994 | RABGGTB | 5876 | 6 | 3 | 44 | |
| GSE60625 | RABGGTB | 5876 | 0 | 0 | 11 | |
| GSE74703 | RABGGTB | 5876 | 2 | 3 | 31 | |
| GSE74704 | RABGGTB | 5876 | 1 | 4 | 15 | |
| TCGA | RABGGTB | 5876 | 8 | 24 | 64 |
Total number of gains: 29; Total number of losses: 59; Total Number of normals: 400.
Somatic mutations of RABGGTB:
Generating mutation plots.
Highly correlated genes for RABGGTB:
Showing top 20/42 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RABGGTB | TSR1 | 0.701117 | 3 | 0 | 3 |
| RABGGTB | MT1HL1 | 0.683703 | 3 | 0 | 3 |
| RABGGTB | SHOC2 | 0.678791 | 4 | 0 | 3 |
| RABGGTB | NCKAP5 | 0.669589 | 3 | 0 | 3 |
| RABGGTB | MT1F | 0.665853 | 3 | 0 | 3 |
| RABGGTB | PRMT9 | 0.640818 | 3 | 0 | 3 |
| RABGGTB | SNX16 | 0.632357 | 3 | 0 | 3 |
| RABGGTB | AGPAT4-IT1 | 0.627693 | 3 | 0 | 3 |
| RABGGTB | UQCRC1 | 0.622157 | 3 | 0 | 3 |
| RABGGTB | PEX6 | 0.607998 | 4 | 0 | 3 |
| RABGGTB | BCAP31 | 0.601217 | 5 | 0 | 5 |
| RABGGTB | UBE2Q1 | 0.596786 | 3 | 0 | 3 |
| RABGGTB | TSLP | 0.590186 | 3 | 0 | 3 |
| RABGGTB | RPS15A | 0.583839 | 4 | 0 | 3 |
| RABGGTB | PDCD11 | 0.583517 | 6 | 0 | 4 |
| RABGGTB | SREK1 | 0.583305 | 5 | 0 | 3 |
| RABGGTB | GEMIN2 | 0.581421 | 4 | 0 | 3 |
| RABGGTB | GPN2 | 0.580997 | 4 | 0 | 3 |
| RABGGTB | SUCLA2 | 0.580937 | 5 | 0 | 3 |
| RABGGTB | LAMTOR5 | 0.578765 | 6 | 0 | 4 |
For details and further investigation, click here
