| Full name: RAN binding protein 2 | Alias Symbol: NUP358|ADANE | ||
| Type: protein-coding gene | Cytoband: 2q13 | ||
| Entrez ID: 5903 | HGNC ID: HGNC:9848 | Ensembl Gene: ENSG00000153201 | OMIM ID: 601181 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RANBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RANBP2 | 5903 | 201713_s_at | 0.2332 | 0.5301 | |
| GSE20347 | RANBP2 | 5903 | 201713_s_at | -0.1432 | 0.2787 | |
| GSE23400 | RANBP2 | 5903 | 201713_s_at | 0.2759 | 0.0013 | |
| GSE26886 | RANBP2 | 5903 | 201713_s_at | -0.3646 | 0.1507 | |
| GSE29001 | RANBP2 | 5903 | 201713_s_at | 0.1731 | 0.4018 | |
| GSE38129 | RANBP2 | 5903 | 201713_s_at | -0.0205 | 0.8791 | |
| GSE45670 | RANBP2 | 5903 | 201713_s_at | 0.0201 | 0.8833 | |
| GSE53622 | RANBP2 | 5903 | 3257 | 0.0049 | 0.9370 | |
| GSE53624 | RANBP2 | 5903 | 3257 | 0.0564 | 0.3556 | |
| GSE63941 | RANBP2 | 5903 | 201713_s_at | -0.7421 | 0.1219 | |
| GSE77861 | RANBP2 | 5903 | 201713_s_at | 0.1167 | 0.7370 | |
| GSE97050 | RANBP2 | 5903 | A_33_P3308740 | 0.3330 | 0.1832 | |
| SRP007169 | RANBP2 | 5903 | RNAseq | 1.2462 | 0.0029 | |
| SRP008496 | RANBP2 | 5903 | RNAseq | 1.5271 | 0.0000 | |
| SRP064894 | RANBP2 | 5903 | RNAseq | -0.1927 | 0.3796 | |
| SRP133303 | RANBP2 | 5903 | RNAseq | 0.1587 | 0.1526 | |
| SRP159526 | RANBP2 | 5903 | RNAseq | -0.0402 | 0.8720 | |
| SRP193095 | RANBP2 | 5903 | RNAseq | -0.1002 | 0.0961 | |
| SRP219564 | RANBP2 | 5903 | RNAseq | -0.3078 | 0.2202 | |
| TCGA | RANBP2 | 5903 | RNAseq | -0.1071 | 0.0088 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RANBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RANBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RANBP2 | 5903 | 4 | 2 | 24 | |
| GSE20123 | RANBP2 | 5903 | 4 | 2 | 24 | |
| GSE43470 | RANBP2 | 5903 | 3 | 1 | 39 | |
| GSE46452 | RANBP2 | 5903 | 1 | 4 | 54 | |
| GSE47630 | RANBP2 | 5903 | 7 | 0 | 33 | |
| GSE54993 | RANBP2 | 5903 | 0 | 6 | 64 | |
| GSE54994 | RANBP2 | 5903 | 10 | 0 | 43 | |
| GSE60625 | RANBP2 | 5903 | 0 | 3 | 8 | |
| GSE74703 | RANBP2 | 5903 | 3 | 1 | 32 | |
| GSE74704 | RANBP2 | 5903 | 2 | 2 | 16 | |
| TCGA | RANBP2 | 5903 | 31 | 6 | 59 |
Total number of gains: 65; Total number of losses: 27; Total Number of normals: 396.
Somatic mutations of RANBP2:
Generating mutation plots.
Highly correlated genes for RANBP2:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RANBP2 | TSR1 | 0.757188 | 3 | 0 | 3 |
| RANBP2 | TRAPPC3L | 0.669793 | 3 | 0 | 3 |
| RANBP2 | MBTD1 | 0.668787 | 4 | 0 | 3 |
| RANBP2 | EDEM3 | 0.652184 | 4 | 0 | 4 |
| RANBP2 | HPDL | 0.642577 | 3 | 0 | 3 |
| RANBP2 | SUMO1 | 0.615727 | 5 | 0 | 4 |
| RANBP2 | C5orf30 | 0.615214 | 5 | 0 | 4 |
| RANBP2 | ZNF30 | 0.609361 | 3 | 0 | 3 |
| RANBP2 | ZDHHC23 | 0.605038 | 3 | 0 | 3 |
| RANBP2 | BCAP31 | 0.600194 | 4 | 0 | 3 |
| RANBP2 | RBM28 | 0.594144 | 5 | 0 | 3 |
| RANBP2 | MAP3K4 | 0.593333 | 4 | 0 | 3 |
| RANBP2 | XRCC2 | 0.58073 | 3 | 0 | 3 |
| RANBP2 | SNX16 | 0.576801 | 3 | 0 | 3 |
| RANBP2 | ZNF329 | 0.571894 | 3 | 0 | 3 |
| RANBP2 | TFDP1 | 0.570354 | 5 | 0 | 3 |
| RANBP2 | PRPF3 | 0.56558 | 5 | 0 | 3 |
| RANBP2 | TBC1D32 | 0.561948 | 3 | 0 | 3 |
| RANBP2 | GPAM | 0.559522 | 5 | 0 | 3 |
| RANBP2 | GCA | 0.557127 | 5 | 0 | 4 |
For details and further investigation, click here
