RABL2A

 

Full name: RAB, member of RAS oncogene family like 2A Alias Symbol: 
Type: protein-coding gene Cytoband: 2q14.1
Entrez ID: 11159 HGNC ID: HGNC:9799 Ensembl Gene: ENSG00000144134 OMIM ID: 605412
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RABL2A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 RABL2A 11159 117662 0.3576 0.0000
GSE53624 RABL2A 11159 117662 0.1815 0.0018
GSE97050 RABL2A 11159 A_33_P3344039 0.1201 0.5891
SRP007169 RABL2A 11159 RNAseq 1.5759 0.0077
SRP064894 RABL2A 11159 RNAseq -0.3000 0.0328
SRP133303 RABL2A 11159 RNAseq -0.1780 0.2833
SRP159526 RABL2A 11159 RNAseq 0.2196 0.4882
SRP193095 RABL2A 11159 RNAseq 0.1429 0.4659
SRP219564 RABL2A 11159 RNAseq -0.0167 0.9606
TCGA RABL2A 11159 RNAseq 0.1299 0.1731

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by RABL2A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RABL2A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RABL2A 11159 7 2 21
GSE20123 RABL2A 11159 7 2 21
GSE43470 RABL2A 11159 3 1 39
GSE46452 RABL2A 11159 1 4 54
GSE47630 RABL2A 11159 6 0 34
GSE54993 RABL2A 11159 0 6 64
GSE54994 RABL2A 11159 11 0 42
GSE60625 RABL2A 11159 0 3 8
GSE74703 RABL2A 11159 3 1 32
GSE74704 RABL2A 11159 3 2 15
TCGA RABL2A 11159 31 6 59

Total number of gains: 72; Total number of losses: 27; Total Number of normals: 389.  

 

Somatic mutations of RABL2A:

 

Generating mutation plots.

 

Highly correlated genes for RABL2A:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RABL2ASEPHS10.712388303
RABL2AMSH60.699405303
RABL2AZNF5940.689287303
RABL2AC2orf680.683365303
RABL2AMCM30.663903303
RABL2ANONO0.656903303
RABL2ACCDC74B0.579948403

For details and further investigation, click here