UBE3D

 

Full name: ubiquitin protein ligase E3D Alias Symbol: DKFZp434A1520|H10BH|YJR141W
Type: protein-coding gene Cytoband: 6q14.1
Entrez ID: 90025 HGNC ID: HGNC:21381 Ensembl Gene: ENSG00000118420 OMIM ID: 612495
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of UBE3D:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UBE3D 90025 227790_at -0.1745 0.6919
GSE26886 UBE3D 90025 227790_at 0.1022 0.6249
GSE45670 UBE3D 90025 227790_at 0.2362 0.1683
GSE53622 UBE3D 90025 60290 0.2606 0.0005
GSE53624 UBE3D 90025 111715 0.1114 0.1338
GSE63941 UBE3D 90025 227790_at -0.5187 0.2302
GSE77861 UBE3D 90025 227790_at -0.0403 0.8471
SRP007169 UBE3D 90025 RNAseq -0.2834 0.5940
SRP008496 UBE3D 90025 RNAseq -0.0502 0.8903
SRP064894 UBE3D 90025 RNAseq 0.0919 0.5993
SRP133303 UBE3D 90025 RNAseq 0.2907 0.0278
SRP159526 UBE3D 90025 RNAseq 0.0007 0.9983
SRP193095 UBE3D 90025 RNAseq 0.0566 0.6841
SRP219564 UBE3D 90025 RNAseq 0.0486 0.9186

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UBE3D expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of UBE3D:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UBE3D 90025 1 4 25
GSE20123 UBE3D 90025 1 3 26
GSE43470 UBE3D 90025 2 1 40
GSE46452 UBE3D 90025 2 11 46
GSE47630 UBE3D 90025 8 6 26
GSE54993 UBE3D 90025 3 2 65
GSE54994 UBE3D 90025 8 8 37
GSE60625 UBE3D 90025 0 1 10
GSE74703 UBE3D 90025 2 1 33
GSE74704 UBE3D 90025 0 2 18
TCGA UBE3D 90025 6 25 65

Total number of gains: 33; Total number of losses: 64; Total Number of normals: 391.  

 

Somatic mutations of UBE3D:

 

Generating mutation plots.

 

Highly correlated genes for UBE3D:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UBE3DDDX11-AS10.625416303
UBE3DLINC009600.564884303
UBE3DDIAPH2-AS10.5636303
UBE3DOBSL10.561686303
UBE3DLINC006220.536764303
UBE3DTHAP60.517171403

For details and further investigation, click here