| Full name: obscurin like 1 | Alias Symbol: KIAA0657 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 23363 | HGNC ID: HGNC:29092 | Ensembl Gene: ENSG00000124006 | OMIM ID: 610991 |
| Drug and gene relationship at DGIdb | |||
Expression of OBSL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OBSL1 | 23363 | 212775_at | 0.0598 | 0.9394 | |
| GSE20347 | OBSL1 | 23363 | 212775_at | 0.5122 | 0.0138 | |
| GSE23400 | OBSL1 | 23363 | 214928_at | -0.1818 | 0.0072 | |
| GSE26886 | OBSL1 | 23363 | 212775_at | 2.0601 | 0.0000 | |
| GSE29001 | OBSL1 | 23363 | 214928_at | -0.1339 | 0.5524 | |
| GSE38129 | OBSL1 | 23363 | 212775_at | 0.4357 | 0.0844 | |
| GSE45670 | OBSL1 | 23363 | 227574_at | -0.2120 | 0.2862 | |
| GSE53622 | OBSL1 | 23363 | 35 | 0.4499 | 0.0000 | |
| GSE53624 | OBSL1 | 23363 | 35 | 0.4629 | 0.0000 | |
| GSE63941 | OBSL1 | 23363 | 227574_at | -0.2197 | 0.6637 | |
| GSE77861 | OBSL1 | 23363 | 227573_s_at | -0.0410 | 0.8002 | |
| GSE97050 | OBSL1 | 23363 | A_23_P300484 | -0.1971 | 0.4882 | |
| SRP007169 | OBSL1 | 23363 | RNAseq | 0.1975 | 0.6097 | |
| SRP008496 | OBSL1 | 23363 | RNAseq | 0.9612 | 0.0358 | |
| SRP064894 | OBSL1 | 23363 | RNAseq | 0.6178 | 0.0080 | |
| SRP133303 | OBSL1 | 23363 | RNAseq | -0.1313 | 0.6062 | |
| SRP159526 | OBSL1 | 23363 | RNAseq | 0.8110 | 0.0598 | |
| SRP193095 | OBSL1 | 23363 | RNAseq | 0.9245 | 0.0000 | |
| SRP219564 | OBSL1 | 23363 | RNAseq | 0.2134 | 0.6923 | |
| TCGA | OBSL1 | 23363 | RNAseq | -0.0831 | 0.3021 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by OBSL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OBSL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OBSL1 | 23363 | 2 | 14 | 14 | |
| GSE20123 | OBSL1 | 23363 | 2 | 13 | 15 | |
| GSE43470 | OBSL1 | 23363 | 1 | 6 | 36 | |
| GSE46452 | OBSL1 | 23363 | 0 | 5 | 54 | |
| GSE47630 | OBSL1 | 23363 | 4 | 5 | 31 | |
| GSE54993 | OBSL1 | 23363 | 1 | 2 | 67 | |
| GSE54994 | OBSL1 | 23363 | 8 | 9 | 36 | |
| GSE60625 | OBSL1 | 23363 | 0 | 3 | 8 | |
| GSE74703 | OBSL1 | 23363 | 1 | 5 | 30 | |
| GSE74704 | OBSL1 | 23363 | 2 | 7 | 11 | |
| TCGA | OBSL1 | 23363 | 13 | 25 | 58 |
Total number of gains: 34; Total number of losses: 94; Total Number of normals: 360.
Somatic mutations of OBSL1:
Generating mutation plots.
Highly correlated genes for OBSL1:
Showing top 20/343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OBSL1 | MEP1B | 0.873379 | 3 | 0 | 3 |
| OBSL1 | C4BPA | 0.843737 | 3 | 0 | 3 |
| OBSL1 | LCT | 0.831207 | 3 | 0 | 3 |
| OBSL1 | AICDA | 0.817269 | 3 | 0 | 3 |
| OBSL1 | HRC | 0.788321 | 3 | 0 | 3 |
| OBSL1 | CCR9 | 0.788081 | 3 | 0 | 3 |
| OBSL1 | RNF17 | 0.78102 | 3 | 0 | 3 |
| OBSL1 | DMC1 | 0.769511 | 3 | 0 | 3 |
| OBSL1 | ZNF446 | 0.756695 | 3 | 0 | 3 |
| OBSL1 | CDH4 | 0.745948 | 4 | 0 | 4 |
| OBSL1 | P2RY4 | 0.744591 | 4 | 0 | 4 |
| OBSL1 | C2CD4D | 0.743226 | 3 | 0 | 3 |
| OBSL1 | FBRSL1 | 0.74271 | 4 | 0 | 3 |
| OBSL1 | SPTA1 | 0.742279 | 4 | 0 | 4 |
| OBSL1 | CELA3B | 0.736809 | 3 | 0 | 3 |
| OBSL1 | DCDC1 | 0.727402 | 3 | 0 | 3 |
| OBSL1 | ACSL6 | 0.722024 | 3 | 0 | 3 |
| OBSL1 | DOHH | 0.719733 | 3 | 0 | 3 |
| OBSL1 | FPR2 | 0.716115 | 3 | 0 | 3 |
| OBSL1 | TEKT2 | 0.7149 | 4 | 0 | 4 |
For details and further investigation, click here
