| Full name: THAP domain containing 6 | Alias Symbol: MGC30052 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 152815 | HGNC ID: HGNC:23189 | Ensembl Gene: ENSG00000174796 | OMIM ID: 612535 |
| Drug and gene relationship at DGIdb | |||
Expression of THAP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP6 | 152815 | 235218_x_at | -0.0393 | 0.8880 | |
| GSE26886 | THAP6 | 152815 | 235218_x_at | 0.0959 | 0.3942 | |
| GSE45670 | THAP6 | 152815 | 227813_at | -0.0839 | 0.6573 | |
| GSE53622 | THAP6 | 152815 | 97372 | 0.3754 | 0.0000 | |
| GSE53624 | THAP6 | 152815 | 80688 | -0.2800 | 0.0029 | |
| GSE63941 | THAP6 | 152815 | 227813_at | -0.3791 | 0.2465 | |
| GSE77861 | THAP6 | 152815 | 235218_x_at | -0.0557 | 0.5403 | |
| GSE97050 | THAP6 | 152815 | A_24_P268893 | -0.1446 | 0.5133 | |
| SRP007169 | THAP6 | 152815 | RNAseq | -0.5071 | 0.1422 | |
| SRP008496 | THAP6 | 152815 | RNAseq | -0.4053 | 0.0893 | |
| SRP064894 | THAP6 | 152815 | RNAseq | -0.0462 | 0.7380 | |
| SRP133303 | THAP6 | 152815 | RNAseq | 0.1296 | 0.5428 | |
| SRP159526 | THAP6 | 152815 | RNAseq | 0.0337 | 0.9071 | |
| SRP193095 | THAP6 | 152815 | RNAseq | -0.1548 | 0.0453 | |
| SRP219564 | THAP6 | 152815 | RNAseq | -0.0864 | 0.7602 | |
| TCGA | THAP6 | 152815 | RNAseq | -0.1272 | 0.0258 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP6 | 152815 | 2 | 9 | 19 | |
| GSE20123 | THAP6 | 152815 | 2 | 9 | 19 | |
| GSE43470 | THAP6 | 152815 | 0 | 13 | 30 | |
| GSE46452 | THAP6 | 152815 | 2 | 35 | 22 | |
| GSE47630 | THAP6 | 152815 | 1 | 19 | 20 | |
| GSE54993 | THAP6 | 152815 | 7 | 0 | 63 | |
| GSE54994 | THAP6 | 152815 | 1 | 9 | 43 | |
| GSE60625 | THAP6 | 152815 | 0 | 0 | 11 | |
| GSE74703 | THAP6 | 152815 | 0 | 11 | 25 | |
| GSE74704 | THAP6 | 152815 | 2 | 5 | 13 | |
| TCGA | THAP6 | 152815 | 17 | 29 | 50 |
Total number of gains: 34; Total number of losses: 139; Total Number of normals: 315.
Somatic mutations of THAP6:
Generating mutation plots.
Highly correlated genes for THAP6:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP6 | ANKRD36B | 0.754929 | 3 | 0 | 3 |
| THAP6 | HAUS2 | 0.735465 | 3 | 0 | 3 |
| THAP6 | MZT2B | 0.732485 | 3 | 0 | 3 |
| THAP6 | TMEM38A | 0.708412 | 3 | 0 | 3 |
| THAP6 | FYTTD1 | 0.706331 | 3 | 0 | 3 |
| THAP6 | RCHY1 | 0.6941 | 3 | 0 | 3 |
| THAP6 | HPS5 | 0.689994 | 4 | 0 | 3 |
| THAP6 | ARL10 | 0.684627 | 3 | 0 | 3 |
| THAP6 | PPIG | 0.681391 | 3 | 0 | 3 |
| THAP6 | ZNF273 | 0.679995 | 3 | 0 | 3 |
| THAP6 | HIPK3 | 0.676152 | 3 | 0 | 3 |
| THAP6 | UBXN2A | 0.674497 | 4 | 0 | 3 |
| THAP6 | ANKRD12 | 0.672594 | 3 | 0 | 3 |
| THAP6 | NMT2 | 0.670548 | 3 | 0 | 3 |
| THAP6 | PGAP1 | 0.66334 | 3 | 0 | 3 |
| THAP6 | IRF7 | 0.663289 | 3 | 0 | 3 |
| THAP6 | ZNF680 | 0.662573 | 3 | 0 | 3 |
| THAP6 | RAMP2-AS1 | 0.651675 | 3 | 0 | 3 |
| THAP6 | DCLRE1C | 0.65148 | 4 | 0 | 3 |
| THAP6 | ATG10 | 0.650755 | 4 | 0 | 3 |
For details and further investigation, click here
