DRC1

 

Full name: dynein regulatory complex subunit 1 Alias Symbol: MGC16372|FLJ32660|CILD21
Type: protein-coding gene Cytoband: 2p23.3
Entrez ID: 92749 HGNC ID: HGNC:24245 Ensembl Gene: ENSG00000157856 OMIM ID: 615288
Drug and gene relationship at DGIdb

 

Expression of DRC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DRC1 92749 231133_at -0.0790 0.7438
GSE26886 DRC1 92749 231133_at 0.0057 0.9632
GSE45670 DRC1 92749 231133_at -0.0155 0.8995
GSE53622 DRC1 92749 6761 -0.3265 0.0004
GSE53624 DRC1 92749 6761 -0.1770 0.0379
GSE63941 DRC1 92749 231133_at 0.1152 0.7356
GSE77861 DRC1 92749 231133_at -0.1042 0.2370

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DRC1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of DRC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DRC1 92749 11 2 17
GSE20123 DRC1 92749 11 2 17
GSE43470 DRC1 92749 3 1 39
GSE46452 DRC1 92749 3 4 52
GSE47630 DRC1 92749 8 0 32
GSE54993 DRC1 92749 0 6 64
GSE54994 DRC1 92749 10 0 43
GSE60625 DRC1 92749 0 3 8
GSE74703 DRC1 92749 3 0 33
GSE74704 DRC1 92749 9 1 10
TCGA DRC1 92749 37 2 57

Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.  

 

Somatic mutations of DRC1:

 

Generating mutation plots.

 

Highly correlated genes for DRC1:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DRC1KRTAP4-120.686988303
DRC1MYL10.571764303
DRC1C11orf530.571679303
DRC1DAOA0.56507303
DRC1VGLL20.560432303
DRC1HTR1E0.55598403
DRC1C2orf720.550846303
DRC1SPATA190.511494403
DRC1MAPT-AS10.501084403

For details and further investigation, click here