C11orf53

 

Full name: chromosome 11 open reading frame 53 Alias Symbol: MGC50104
Type: protein-coding gene Cytoband: 11q23.1
Entrez ID: 341032 HGNC ID: HGNC:30527 Ensembl Gene: ENSG00000150750 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C11orf53:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C11orf53 341032 1554188_at -0.0167 0.9464
GSE26886 C11orf53 341032 1554188_at 0.2783 0.0220
GSE45670 C11orf53 341032 1554188_at -0.0305 0.7865
GSE53622 C11orf53 341032 27701 0.7236 0.0077
GSE53624 C11orf53 341032 27701 1.2296 0.0000
GSE63941 C11orf53 341032 1554188_at 0.4431 0.4672
GSE77861 C11orf53 341032 1554188_at -0.1801 0.0532
TCGA C11orf53 341032 RNAseq -1.6168 0.0771

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by C11orf53 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C11orf53:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C11orf53 341032 0 13 17
GSE20123 C11orf53 341032 0 12 18
GSE43470 C11orf53 341032 2 6 35
GSE46452 C11orf53 341032 3 26 30
GSE47630 C11orf53 341032 2 19 19
GSE54993 C11orf53 341032 10 0 60
GSE54994 C11orf53 341032 5 19 29
GSE60625 C11orf53 341032 0 3 8
GSE74703 C11orf53 341032 1 4 31
GSE74704 C11orf53 341032 0 8 12
TCGA C11orf53 341032 6 47 43

Total number of gains: 29; Total number of losses: 157; Total Number of normals: 302.  

 

Somatic mutations of C11orf53:

 

Generating mutation plots.

 

Highly correlated genes for C11orf53:

 

Showing all 14 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C11orf53COL4A40.747303
C11orf53MYL6B0.649251303
C11orf53ARL6IP40.613193303
C11orf53ZSCAN10.582028303
C11orf53DRC10.571679303
C11orf53OR2H10.553084303
C11orf53ACE20.549976303
C11orf53NPY0.549135303
C11orf53ASMTL-AS10.547696303
C11orf53SYT80.545743403
C11orf53LINC011340.534083403
C11orf53LINC012890.523394403
C11orf53MUC130.507777403
C11orf53KRTAP5-AS10.503302403

For details and further investigation, click here