| Full name: D-amino acid oxidase activator | Alias Symbol: G72 | ||
| Type: protein-coding gene | Cytoband: 13q33.2 | ||
| Entrez ID: 267012 | HGNC ID: HGNC:21191 | Ensembl Gene: ENSG00000182346 | OMIM ID: 607408 |
| Drug and gene relationship at DGIdb | |||
Expression of DAOA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DAOA | 267012 | 1555662_s_at | -0.1013 | 0.6351 | |
| GSE26886 | DAOA | 267012 | 1555662_s_at | 0.1154 | 0.3008 | |
| GSE45670 | DAOA | 267012 | 1555662_s_at | 0.0328 | 0.8125 | |
| GSE53622 | DAOA | 267012 | 22798 | 0.4916 | 0.0000 | |
| GSE53624 | DAOA | 267012 | 22798 | 0.5615 | 0.0001 | |
| GSE63941 | DAOA | 267012 | 1555662_s_at | 0.0250 | 0.8942 | |
| GSE77861 | DAOA | 267012 | 1555640_at | -0.1108 | 0.3116 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DAOA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DAOA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DAOA | 267012 | 6 | 10 | 14 | |
| GSE20123 | DAOA | 267012 | 6 | 9 | 15 | |
| GSE43470 | DAOA | 267012 | 4 | 11 | 28 | |
| GSE46452 | DAOA | 267012 | 1 | 31 | 27 | |
| GSE47630 | DAOA | 267012 | 3 | 26 | 11 | |
| GSE54993 | DAOA | 267012 | 11 | 4 | 55 | |
| GSE54994 | DAOA | 267012 | 8 | 8 | 37 | |
| GSE60625 | DAOA | 267012 | 0 | 3 | 8 | |
| GSE74703 | DAOA | 267012 | 3 | 9 | 24 | |
| GSE74704 | DAOA | 267012 | 4 | 9 | 7 | |
| TCGA | DAOA | 267012 | 15 | 35 | 46 |
Total number of gains: 61; Total number of losses: 155; Total Number of normals: 272.
Somatic mutations of DAOA:
Generating mutation plots.
Highly correlated genes for DAOA:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DAOA | RPRML | 0.763084 | 3 | 0 | 3 |
| DAOA | LINC01352 | 0.753186 | 3 | 0 | 3 |
| DAOA | SYCN | 0.717554 | 3 | 0 | 3 |
| DAOA | PRKCG | 0.702815 | 3 | 0 | 3 |
| DAOA | ST8SIA3 | 0.700974 | 3 | 0 | 3 |
| DAOA | LINC01398 | 0.700949 | 3 | 0 | 3 |
| DAOA | RASL10B | 0.692515 | 3 | 0 | 3 |
| DAOA | PDHA2 | 0.692158 | 3 | 0 | 3 |
| DAOA | COX6A2 | 0.683247 | 3 | 0 | 3 |
| DAOA | HIPK1-AS1 | 0.680591 | 3 | 0 | 3 |
| DAOA | CT62 | 0.678699 | 3 | 0 | 3 |
| DAOA | CIB3 | 0.677029 | 4 | 0 | 4 |
| DAOA | TNNI1 | 0.676639 | 4 | 0 | 4 |
| DAOA | LINC01281 | 0.675442 | 3 | 0 | 3 |
| DAOA | LINC00620 | 0.674314 | 3 | 0 | 3 |
| DAOA | ATCAY | 0.671053 | 4 | 0 | 4 |
| DAOA | LINC00894 | 0.667939 | 4 | 0 | 3 |
| DAOA | MAGEC1 | 0.667877 | 3 | 0 | 3 |
| DAOA | BFSP2-AS1 | 0.660591 | 4 | 0 | 3 |
| DAOA | CCDC154 | 0.659914 | 4 | 0 | 3 |
For details and further investigation, click here
