HEPHL1

 

Full name: hephaestin like 1 Alias Symbol: DKFZp686F22190
Type: protein-coding gene Cytoband: 11q21
Entrez ID: 341208 HGNC ID: HGNC:30477 Ensembl Gene: ENSG00000181333 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of HEPHL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 HEPHL1 341208 51200 1.1931 0.0021
GSE53624 HEPHL1 341208 51200 0.5918 0.0122
GSE97050 HEPHL1 341208 A_33_P3215043 1.0643 0.1403
SRP007169 HEPHL1 341208 RNAseq -1.6221 0.0005
SRP008496 HEPHL1 341208 RNAseq -1.2425 0.2803
SRP064894 HEPHL1 341208 RNAseq 1.0689 0.0729
SRP133303 HEPHL1 341208 RNAseq 2.5146 0.0000
SRP159526 HEPHL1 341208 RNAseq -0.8679 0.3363
SRP219564 HEPHL1 341208 RNAseq -0.7079 0.5746
TCGA HEPHL1 341208 RNAseq 1.8456 0.0000

Upregulated datasets: 3; Downregulated datasets: 1.  

 

Survival by HEPHL1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HEPHL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HEPHL1 341208 3 9 18
GSE20123 HEPHL1 341208 3 9 18
GSE43470 HEPHL1 341208 2 5 36
GSE46452 HEPHL1 341208 5 24 30
GSE47630 HEPHL1 341208 2 19 19
GSE54993 HEPHL1 341208 8 2 60
GSE54994 HEPHL1 341208 5 19 29
GSE60625 HEPHL1 341208 0 3 8
GSE74703 HEPHL1 341208 1 4 31
GSE74704 HEPHL1 341208 3 5 12
TCGA HEPHL1 341208 12 42 42

Total number of gains: 44; Total number of losses: 141; Total Number of normals: 303.  

 

Somatic mutations of HEPHL1:

 

Generating mutation plots.

 

Highly correlated genes for HEPHL1:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HEPHL1IL36G0.729117303
HEPHL1KRTDAP0.707838303
HEPHL1LYPD50.647321303
HEPHL1SLC28A30.641389303
HEPHL1SERPINB70.622796303
HEPHL1FAM83A0.590776303
HEPHL1FAM83B0.537627303

For details and further investigation, click here