| Full name: keratinocyte differentiation associated protein | Alias Symbol: KDAP|UNQ467 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 388533 | HGNC ID: HGNC:16313 | Ensembl Gene: ENSG00000188508 | OMIM ID: 617212 |
| Drug and gene relationship at DGIdb | |||
Expression of KRTDAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTDAP | 388533 | 230835_at | 0.7932 | 0.8114 | |
| GSE26886 | KRTDAP | 388533 | 230835_at | -0.8326 | 0.4407 | |
| GSE45670 | KRTDAP | 388533 | 230835_at | 3.9810 | 0.0000 | |
| GSE53622 | KRTDAP | 388533 | 152511 | 2.1837 | 0.0000 | |
| GSE53624 | KRTDAP | 388533 | 152511 | 1.4374 | 0.0000 | |
| GSE63941 | KRTDAP | 388533 | 230835_at | 0.9108 | 0.2153 | |
| GSE77861 | KRTDAP | 388533 | 230835_at | 0.5891 | 0.5793 | |
| GSE97050 | KRTDAP | 388533 | A_23_P90453 | 2.7602 | 0.1291 | |
| SRP007169 | KRTDAP | 388533 | RNAseq | 1.1817 | 0.1478 | |
| SRP008496 | KRTDAP | 388533 | RNAseq | -0.2059 | 0.7866 | |
| SRP064894 | KRTDAP | 388533 | RNAseq | 2.1915 | 0.0115 | |
| SRP133303 | KRTDAP | 388533 | RNAseq | 2.6172 | 0.0082 | |
| SRP159526 | KRTDAP | 388533 | RNAseq | 2.7446 | 0.0155 | |
| TCGA | KRTDAP | 388533 | RNAseq | 1.1973 | 0.0186 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by KRTDAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTDAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTDAP | 388533 | 6 | 4 | 20 | |
| GSE20123 | KRTDAP | 388533 | 6 | 3 | 21 | |
| GSE43470 | KRTDAP | 388533 | 3 | 7 | 33 | |
| GSE46452 | KRTDAP | 388533 | 48 | 1 | 10 | |
| GSE47630 | KRTDAP | 388533 | 9 | 5 | 26 | |
| GSE54993 | KRTDAP | 388533 | 17 | 3 | 50 | |
| GSE54994 | KRTDAP | 388533 | 8 | 9 | 36 | |
| GSE60625 | KRTDAP | 388533 | 9 | 0 | 2 | |
| GSE74703 | KRTDAP | 388533 | 3 | 4 | 29 | |
| GSE74704 | KRTDAP | 388533 | 6 | 1 | 13 | |
| TCGA | KRTDAP | 388533 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of KRTDAP:
Generating mutation plots.
Highly correlated genes for KRTDAP:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTDAP | SPRR2G | 0.726801 | 8 | 0 | 8 |
| KRTDAP | TUSC3 | 0.709387 | 3 | 0 | 3 |
| KRTDAP | HEPHL1 | 0.707838 | 3 | 0 | 3 |
| KRTDAP | AKR1C2 | 0.704116 | 3 | 0 | 3 |
| KRTDAP | LCE3D | 0.692418 | 8 | 0 | 7 |
| KRTDAP | ALOXE3 | 0.686594 | 7 | 0 | 6 |
| KRTDAP | PLA2G4E | 0.684722 | 3 | 0 | 3 |
| KRTDAP | RDH11 | 0.682392 | 4 | 0 | 4 |
| KRTDAP | PDPN | 0.672086 | 3 | 0 | 3 |
| KRTDAP | TMEM45A | 0.671224 | 6 | 0 | 5 |
| KRTDAP | IL36G | 0.669404 | 7 | 0 | 5 |
| KRTDAP | ALOX12B | 0.665973 | 7 | 0 | 6 |
| KRTDAP | DLX5 | 0.660463 | 7 | 0 | 6 |
| KRTDAP | CDSN | 0.659646 | 8 | 0 | 7 |
| KRTDAP | SERPINB7 | 0.65894 | 6 | 0 | 5 |
| KRTDAP | CEACAM19 | 0.65517 | 7 | 0 | 5 |
| KRTDAP | CDKN3 | 0.653783 | 3 | 0 | 3 |
| KRTDAP | KRT16 | 0.651836 | 9 | 0 | 9 |
| KRTDAP | PYCARD | 0.650868 | 4 | 0 | 3 |
| KRTDAP | FABP4 | 0.650766 | 3 | 0 | 3 |
For details and further investigation, click here
